Total sleep deprivation alters spontaneous brain activity in medical staff during routine clinical work: a resting-state functional MR imaging study
Cong Peng,
Dingbo Guo,
Liuheng Liu
et al.
Abstract:ObjectivesTo assess the effect of total sleep deprivation (TSD) on spontaneous brain activity in medical staff during routine clinical practice.MethodsA total of 36 medical staff members underwent resting-state functional MRI (rs-fMRI) scans and neuropsychological tests twice, corresponding to rested wakefulness (RW) after normal sleep and 24 h of acute TSD. The rs-fMRI features, including the mean fractional amplitude of low-frequency fluctuation (mfALFF), z-score transformed regional homogeneity (zReHo), and… Show more
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