“…1,2 Despite a low rate of recurrence and satisfactory results, 3,4 more than 20% of patients with an open mastoid cavity experience intermitted or continuous otorrhea, 5,6 which is often resistant to therapy. 7 It seems that a major problem of unstable cavities is insufficient (re)epithelialization, 8 which is favored by local conditions, unfavorable cavity shape, and size 9,10 and host factors. 11 Recently we presented promising results with the topical treatment of chronically discharging open mastoid cavities with honey gel, which led to less discomfort, otorrhea, inflammation, and infection than conventional eardrops.…”