Total mesoesophagus excision by thoracoscopy and laparoscopy in the radical resection of esophageal carcinoma

Li, Zhuo-Yi; Fu, Junhui; Du, Ze-Sen

doi:10.21037/jtd.2019.07.18

Cited by 1 publication

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Motivated by results of total mesorectal excision for rectal cancer from the point of view of reducing CRM rates and locoregional recurrences 19 , there has been a growing evidence suggesting existence of "Mesoesophagus". [20][21][22] The procedure has been named as Total Mesoesophageal excision (TME). 21,23 TME for esophageal cancer appears to decrease the incidence of locoregional recurrence by reducing the rates of CRM positivity.…”

Section: Bpkmchmentioning

confidence: 99%

Importance of Circumferential Resection Margin in Management of Esophageal Cancer

Thakur

Devkota

et al. 2020

Nep. J. Cancer

View full text Add to dashboard Cite

Esophagectomy (R0) remains the gold standard for the management of esophageal cancer. But due to close vicinity of esophagus with the major structures like heart, aorta, vertebral column, tracheobronchial tree and lungs, a wider circumferential resection is generally not possible and a R1/ R2 resection might occur. Therefore, locoregional recurrence rates of esophageal cancer are reported to be as high as 52%. The Royal College of Pathologists (RCP) and The College of American Pathologists (CAP) define circumferential resection margin (CRM) differently. A mean overall CRM involvement was found to be 40.7% (RCP criteria) and 11.8% (CAP criteria). Twometa-analyses have shown poor survival in CRM positive cases. CRM positivity in T1/ T2 lesions should not occur unless there is a surgical fault. For T3 lesions, a higher rate of CRM positivity has been documented. Therefore, a wider CRM using transthoracic approach appears mandatory, especially for T3 lesions.

show abstract