Total mandibular reconstruction following diffuse sclerosing osteomyelitis

Rustemeyer, Jan; Siegmund, Birte Julia; Okcu, Yunus; Busch, Alexander

doi:10.1007/s10006-018-0731-9

Cited by 21 publications

(15 citation statements)

References 11 publications

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“…Some articles reported concomitant mandibular and condyle reconstruction (Landes et al, 2014; Rodrigues et al, 2015; Rustemeyer, Siegmund, Okcu, & Busch, 2019; Sarlabous & Psutka, 2018). But it was with fibula or iliac crest free flap or nonvascularized iliac crest bone graft (Landes et al, 2014; Rodrigues et al, 2015; Rustemeyer et al, 2019; Sarlabous & Psutka, 2018). No article reports a total mandibular reconstruction with both condyles in one‐step procedure.…”

Section: Discussionmentioning

confidence: 99%

“…Rustemeyer et al described a total mandibular reconstruction including both condyles with alloplastic TMJ prosthesis and two free fibular flaps (Rustemeyer et al, 2019). However, it was a four‐step procedure over several years: first the reconstruction of the right hemi‐mandible, then the reconstruction of the left hemi‐mandible, then the reconstruction of the right TMJ and finally the reconstruction of the left TMJ.…”

Section: Discussionmentioning

confidence: 99%

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One stage microvascular mandible reconstruction by using scapula chimeric flap combined with computer‐aided‐design and computer‐aided‐manufacturing plate including bilateral alloplastic TMJ prosthesis: A case report

et al. 2020

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This report focuses a defect comprising the complete mandible due to osteonecrosis, including both condyles, that required bilateral temporomandibular joint (TMJ) reconstruction with complete mandibular corpus using a computer‐aided‐design and computer‐aided‐manufacturing(CAD‐CAM) planning to harvest a scapula chimeric free flap combined with plate including bilateral alloplastic TMJ prosthesis. This procedure was realized in one and the same surgery. A 73 year‐old‐man developed an osteoradionecrosis of the total mandible including both condyles after radiation therapy for a squamous cell carcinoma of the tongue base(cT4aN2bM0G3). A CAD‐CAM reconstruction was planned with a plate extended by bilateral individual TMJ prosthesis, individual fossa components and combined with a composite free flap originating from the subscapular vessel system including scapula(circumflex subscapular artery) for reconstruction of the mandibular corpus which was osteotomized in three segments with a resection guide, the parascapular skin paddle (descending branch of circumflex subscapular artery) for compensation of the soft tissue deficiency of the cervical skin and latissimus dorsi muscle(thoracodorsal artery) for the inner mucosal lining and intraoral reconstruction. The subscapular artery was anastomosed to the external carotid artery and two concomitant veins were sutured end‐to‐side to the internal jugular vein. The patient was discharged without feeding tube and tracheostomy. No complications have been observed after 6 months follow‐up. The patient was able to tolerate soft diet and had comprehensible speech. Thus, a total mandibular reconstruction including both condyles using alloplastic and autoplastic reconstruction in one and the same stage is a valid option and may be considered in comparably severe cases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

One stage microvascular mandible reconstruction by using scapula chimeric flap combined with computer‐aided‐design and computer‐aided‐manufacturing plate including bilateral alloplastic TMJ prosthesis: A case report

et al. 2020

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“…The current literature overall describes surgical procedures ranging from decortications to partial resections of the mandible [4,17,[26][27][28][29]. In the present data included, only Jacobsson and Hollender reported a surgical procedure as part of the treatment protocol.…”

Section: Surgical Therapymentioning

confidence: 98%

“…Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory disease of unclear etiology. The association of CNO with various diseases, including inflammatory, rheumatic, dermatological, and inflammatory bowel diseases (IBD), is reported [1][2][3][4][5][6]. Cytokine imbalance appears to be the decisive factor in CNO pathogenesis.…”

Section: Introductionmentioning

confidence: 99%

“…To date, there are no specific guidelines for the treatment of chronic non-bacterial osteomyelitis in adult patients. The therapeutic strategies described in the literature range from conservative functional therapy and drug therapy with non-steroidal anti-inflammatory drugs (NSAIDs) to complete resection of the mandible with plastic reconstruction [4,17,20]. Since the disease is rarely diagnosed in adult patients, randomized clinical trials are scarce.…”

Section: Introductionmentioning

confidence: 99%

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Response of Different Treatment Protocols to Treat Chronic Non-Bacterial Osteomyelitis (CNO) of the Mandible in Adult Patients: A Systematic Review

Timme

Bohner

Huss

et al. 2020

IJERPH

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(1) Background: Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory bone disease of finally unknown etiology, which can occur alone or related with syndromes (chronic recurrent multifocal osteomyelitis—CRMO; synovitis, acne, pustulosis, hyperostosis and osteitis syndrome—SAPHO). The involvement of the mandible is rather rare. (2) Methods: We carried out a systematic literature search on CNO with mandibular involvement, according to the “Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA) guidelines, considering the different synonyms for CNO, with a special focus on therapy. (3) Results: Finally, only four studies could be included. A total of 36 patients were treated in these studies—therefore, at most, only tendencies could be identified. The therapy in the included works was inconsistent. Various therapies could alleviate the symptoms of the disease. A complete remission could only rarely be observed and is also to be viewed against the background of the fluctuating character of the disease. The success of one-off interventions is unlikely overall, and the need for long-term therapies seems to be indicated. Non-steroidal anti-inflammatory drugs (NSAIDs) were not part of any effective therapy. Surgical therapy should not be the first choice. (4) Conclusions: In summary, no evidence-based therapy recommendation can be given today. For the future, systematic clinical trials on therapy for CNO are desirable.

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Near‐total mandibular reconstruction following osteoradionecrosis with double scapula tip free flap: A case report

2021

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Near-total mandibular reconstruction poses many challenges to reconstructive surgeons. The purpose of this article is to present a challenging case in a patient with osteoradionecrosis of the mandible requiring a near-total mandibular reconstruction using bilateral scapula tip free tissue reconstruction. A 68-year-old African-American male with a history of T2N0M0 squamous cell carcinoma of the tonsil presented with advanced stage osteoradionecrosis of the mandible. Reconstruction was planned using 3D Systems (Denver, CO), mandibular osteotomies were planned inferior to the sigmoid notch on the ascending rami. Neither fibula flap was amenable for harvesting due to poor vasculature of the patient's lower extremities, and bilateral scapula tip free flaps were subsequently planned. The post-operative course was complicated by venous congestion in the right scapula flap which required revision to the venous anastomosis on POD 1. The patient had intraoral breakdown that required debridement in the operating room and application of a cellular matrix. The

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Total mandibular reconstruction following diffuse sclerosing osteomyelitis

Cited by 21 publications

References 11 publications

One stage microvascular mandible reconstruction by using scapula chimeric flap combined with computer‐aided‐design and computer‐aided‐manufacturing plate including bilateral alloplastic TMJ prosthesis: A case report

One stage microvascular mandible reconstruction by using scapula chimeric flap combined with computer‐aided‐design and computer‐aided‐manufacturing plate including bilateral alloplastic TMJ prosthesis: A case report

Response of Different Treatment Protocols to Treat Chronic Non-Bacterial Osteomyelitis (CNO) of the Mandible in Adult Patients: A Systematic Review

Near‐total mandibular reconstruction following osteoradionecrosis with double scapula tip free flap: A case report

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