Total knee arthroplasty in haemophilic arthropathy with severe flexion deformity and <scp>HIV</scp>–<scp>TB</scp> co‐infection: a case report

Mohanty, Shubhranshu S.; Dash, Kumar Kaushik

doi:10.1111/hae.12157

Cited by 2 publications

(3 citation statements)

References 18 publications

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“…Infection is a significant concern in HPs undergoing TKA and is more frequent in HPs than in the general population, 24 reported as up to 17% in this population 25 . No relationship has been found between infection prevalence and HIV status in HPs 26 . Panotopoulos et al 18 performed a regression analysis and did not identify any correlated factors for infection in HPs.…”

Section: Discussionmentioning

confidence: 99%

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Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty

Oyarzun¹,

Barrientos

Barahona

et al. 2020

Haemophilia

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Introduction: Total knee arthroplasty (TKA) can improve knee function in the general population, but challenges arise for TKA use in haemophilic patients (HPs). Aim: This study aimed to evaluate the midterm clinical experience of a single medical centre in TKA in HPs. Methods: We performed a case series of consecutive TKAs from 2007 to 2013 in HPs. All patients received coagulation factor supplementation according to the institutional protocol. Surgery was performed without a tourniquet by a standard midline medial parapatellar approach. We compared the range of motion (ROM) and flexion contracture before surgery and 1-year postoperative using paired Wilcoxon-nonparametric test (P < .05 was considered significant). The need for revision surgery was considered TKA survival failure. Results: Forty-one HP/60 TKAs were reviewed (19 cases were bilateral). Preoperative median ROM and flexion contracture was 75° (range, 0°-95°) and 20° (range, 5°-80°), respectively. The postoperative median ROM increased to 83° (range, 45°-110°), and median flexion contracture decrease to 0° (range, 0°-40°) a statistically significant difference (P < .01). Postoperative median clinical Knee Society Score (KSS) and functional KSS were 88 (range, 59-97) and 100 (range, 30-100), respectively. Six patients required revision (6.66%) due to infection. TKA survival at 5 years was 92% (range, 82%-96%). Conclusion: This study supports that TKA improves function and ROM in haemophilic knee arthropathy. The protocol of coagulation factors used in this cohort is valid as no related complications were reported. A higher incidence of complications, especially infections, must be expected compared with a TKA in non-HPs. K E Y W O R D S haemophilic knee arthropathy, simultaneous bilateral TKA, TKA complications, TKA survival, total knee arthroplasty e180 | OYARZUN et Al. How to cite this article: Oyarzun A, Barrientos C, Barahona M, et al. Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty.

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Section: Discussionmentioning

confidence: 99%

“…25 No relationship has been found between infection prevalence and HIV status in HPs. 26 Panotopoulos et al 18 performed a regression analysis and did not identify any correlated factors for infection in HPs. All possible action must be considered to avoid infection in any patient, but especially for HPs.…”

Section: Rom Distribuɵon F I G U R Ementioning

confidence: 99%

Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty

Oyarzun¹,

Barrientos

Barahona

et al. 2020

Haemophilia

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“…However, these data may be biased by the confounding effect of hemophilia among historical cohorts of patients with HIV [9]. Moreover, existing data on infection and other complications in patients with HIV have been limited by small sample sizes with low statistical power [2,9,11,12,14,21].…”

Section: Introductionmentioning

confidence: 99%

Does HIV Infection Increase the Risk of Perioperative Complications After THA? A Nationwide Database Study

Naziri

Boylan

Issa

et al. 2015

Clinical Orthopaedics &Amp; Related Research

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Total knee arthroplasty in haemophilic arthropathy with severe flexion deformity and HIV–TB co‐infection: a case report

Cited by 2 publications

References 18 publications

Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty

Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty

Does HIV Infection Increase the Risk of Perioperative Complications After THA? A Nationwide Database Study

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