Total knee arthroplasty improves gait adaptability in osteoarthritis patients; a pilot study

Booij, M.J.; Royen, Barend J. van; Nolte, Peter A.; Twisk, J.W.R.; Harlaar, Jaap; Noort, Josien C. van den

doi:10.1016/j.jor.2022.08.003

Cited by 3 publications

(1 citation statement)

References 24 publications

(42 reference statements)

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“…Osteoarthritis of the knee is common. [1][2][3] Especially after early sports traumata with persisting cartilage injuries, OA can also manifest itself much earlier. [4][5][6][7] If conservative treatment fails, partial or total knee arthroplasty is often performed.…”

Section: Introductionmentioning

confidence: 99%

Fostering Excellence in Knee Arthroplasty: Developing Optimal Patient Care Pathways and Inspiring Knowledge Transfer of Advanced Surgical Techniques

Migliorini,

Feierabend,

Hofmann

2023

JHL

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Osteoarthritis of the knee is common. Early sports trauma or cartilage defects are risk factors for osteoarthritis. If conservative treatment fails, partial or total joint replacement is often performed. A joint replacement aims to restore physiological biomechanics and the quality of life of affected patients. Total knee arthroplasty is one of the most performed surgeries in musculoskeletal medicine. Several developments have taken place over the last decades that have truly altered the way we look at knee arthroplasty today. Some of the fascinating aspects will be presented and discussed in the present narrative review.

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Section: Introductionmentioning

confidence: 99%

Fostering Excellence in Knee Arthroplasty: Developing Optimal Patient Care Pathways and Inspiring Knowledge Transfer of Advanced Surgical Techniques

Migliorini,

Feierabend,

Hofmann

2023

JHL

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Identifying patient subgroups with different trends of patient-reported outcomes (PROMs) after elective knee arthroplasty

Golinelli

Grassi

Sanmarchi

et al. 2023

BMC Musculoskelet Disord

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Background Patient-reported outcome measures (PROMs) are increasingly being used to assess the effectiveness of elective total knee arthroplasty (TKA). However, little is known about how PROMs scores change over time in these patients. The aim of this study was to identify the trajectories of quality of life and joint functioning, and their associated demographic and clinical features in patients undergoing elective TKA. Methods A prospective, cohort study was conducted, in which PROMs questionnaires (Euro Quality 5 Dimensions 3L, EQ-5D-3L, and Knee injury and Osteoarthritis Outcome Score Patient Satisfaction, KOOS-PS) were administered to patients at a single center undergoing elective TKA before surgery, and at 6 and 12 months after surgery. Latent class growth mixture models were used to analyze the patterns of change in PROMs scores over time. Multinomial logistic regression was used to investigate the association between patient characteristics and PROMs trajectories. Results A total of 564 patients were included in the study. The analysis highlighted differential patterns of improvement after TKA. Three distinct PROMs trajectories were identified for each PROMs questionnaire, with one trajectory indicating the most favorable outcome. Female gender appears to be associated with a presentation to surgery with worse perceived quality of life and joint function than males, but also more rapid improvement after surgery. Having an ASA score greater than 3 is instead associated with a worse functional recovery after TKA. Conclusion The results suggest three main PROMs trajectories in patients undergoing elective TKA. Most patients reported improved quality of life and joint functioning at 6 months, which then stabilized. However, other subgroups showed more varied trajectories. Further research is needed to confirm these findings and to explore the potential clinical implications of these results.

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Identifying patient subgroups with different trends of patient-reported outcomes (PROMs) after elective knee arthroplasty

Golinelli

Grassi

Sanmarchi

et al. 2023

Preprint

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Background Patient-reported outcome measures (PROMs) are increasingly being used to assess the effectiveness of elective total knee arthroplasty (TKA). However, little is known about the change over time of PROMs scores in these patients. The aim of this study was to identify the trajectories of quality of life and joint functioning, and their associated demographic and clinical features in patients undergoing elective TKA. Methods We conducted a prospective, cohort study in which PROMs questionnaires (Euro Quality 5 Dimensions 3L, EQ-5D-3L, and Knee injury and Osteoarthritis Outcome Score Patient Satisfaction, KOOS-PS) were administered to patients undergoing elective TKA before surgery, and at 6 and 12 months after surgery at a single center. Latent class growth mixture models were used to analyze the patterns of change in PROMs scores over time. Multinomial logistic regression was used to investigate the association between patient characteristics and PROMs trajectories. Results A total of 564 patients were included in the study. Our analysis highlighted differential patterns of improvement after TKA. Three distinct PROMs trajectories were identified for each PROMs questionnaire, with one trajectory characterizing the best outcome. Female gender appears to be associated with a presentation to surgery with worse perceived quality of life and joint function than males, but also more rapid improvement after surgery. Having an ASA score greater than 3 is instead associated with a worse functional recovery after TKA. Conclusion Our results suggest three main PROMs trajectories in patients undergoing elective TKA. Most patients reported an increase in quality of life and joint functioning at 6 months and a stabilization afterwards, while other subgroups present more heterogeneous trajectories. Further research is needed to confirm these findings and to explore the potential clinical implications of these results.

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Total knee arthroplasty improves gait adaptability in osteoarthritis patients; a pilot study

Cited by 3 publications

References 24 publications

Fostering Excellence in Knee Arthroplasty: Developing Optimal Patient Care Pathways and Inspiring Knowledge Transfer of Advanced Surgical Techniques

Fostering Excellence in Knee Arthroplasty: Developing Optimal Patient Care Pathways and Inspiring Knowledge Transfer of Advanced Surgical Techniques

Identifying patient subgroups with different trends of patient-reported outcomes (PROMs) after elective knee arthroplasty

Identifying patient subgroups with different trends of patient-reported outcomes (PROMs) after elective knee arthroplasty

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