Total heterotopic ossification of an acellular dermal matrix used for abdominal wall reconstruction

Tam, Vernissia; Zelken, Jonathan; Sacks, Justin M.

doi:10.1136/bcr-2013-009081

Cited by 5 publications

(6 citation statements)

References 7 publications

(8 reference statements)

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“…Invasive treatment is considered unnecessary for asymptomatic patients [ 17 ]. Noninvasive treatments, such as non-steroidal anti-inflammatory drugs (e.g., ibuprofen, indomethacin), diphosphonates (etidronate), or radiation therapy have been reported in early studies [ 2 , 7 , 10 ], but are rarely seen in recent literature [ 13 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

Heterotopic Mesenteric Ossification With Trilineage Hematopoiesis

Martinbianco¹,

Lilley²,

Grech³

et al. 2022

Cureus

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Heterotopic ossification (HO) histologically refers to extraskeletal bone formation in non-ossifying tissues, most commonly noted in the extremities, buttocks, abdominal wall, and hip joints. HO developing in the mesentery (heterotopic mesenteric ossification, HMO) is very rare, with fewer than 100 cases reported in the literature. It usually occurs in adult male patients with a history of repeated abdominal trauma. So far, only two cases of HMO have been reported with the development of hematopoietic bone marrow. Here, we report the third case of HMO with true trilineage hematopoiesis in a 66-year-old female with suspicious mesenteric-retained foreign material from prior surgical procedures, including hysterectomy for endometrial adenocarcinoma and multiple repairs for incisional hernia.

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Section: Discussionmentioning

confidence: 99%

Heterotopic Mesenteric Ossification With Trilineage Hematopoiesis

Martinbianco¹,

Lilley²,

Grech³

et al. 2022

Cureus

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“…There was no recurrence at 6 months. 5 No other cases with heterotopic ossification in patients with ADM reconstruction have been described.…”

Section: Discussionmentioning

confidence: 99%

“… 1 There is a predilection for upper midline incisions; however, symptomatic heterotopic ossification of the abdominal wall seems to be much less common, with only single cases and small case series reported. 2 – 5 …”

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confidence: 99%

Extensive Abdominal Wall Incisional Heterotopic Ossification Reconstructed with Component Separation and Strattice Inlay

Suleiman

Sandberg

2016

Plastic and Reconstructive Surgery - Global Open

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Summary:Symptomatic heterotopic ossification of abdominal surgical incisions is a rare occurrence. We present a 67-year-old man with severe discomfort caused by heterotopic ossification extending from the xiphoid to the umbilicus. The patient underwent an abdominal aortic aneurysm repair 3 years before our treatment. A 13 × 3.5 cm ossified lesion was excised. The resulting midline defect was closed using component separation and inlay Strattice. Tension-free midline adaptation of the recti muscles was achieved. A computed tomography scan of the abdomen 6 months after the surgery showed no recurrence or hernias. Heterotopic ossification in symptomatic patients has previously been treated with excision and primary closure. We believe that tension-free repair is important to prevent recurrence. Acellular dermal matrix may add to this effect and also compartmentalize the process.

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“…There are approximately 30 cases of heterotopic mesenteric ossification described in the literature to date, the majority of which are related to abdominal surgery. 1,7,8,8–12 Males are affected 1.5 times more frequently than females, most commonly in mid to late adulthood. 1,11 Presenting symptoms are usually consistent with small bowel obstruction, including nausea/vomiting, abdominal distention, and obstipation.…”

Section: Discussionmentioning

confidence: 99%

Mesenteric calcification following abdominal stab wound

Hicks

Velopulos

Sacks

2014

International Journal of Surgery Case Reports

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INTRODUCTIONHeterotopic ossification (HO) refers to the formation of bone in non-ossifying tissue. Heterotopic mesenteric ossification is a rare form of HO that is characterized by the formation of an ossifying pseudotumour at the base of the mesentery, usually following abdominal surgery.PRESENTATION OF CASEWe describe a case of mesenteric HO in a young male who presented for elective ventral incisional hernia repair following a stab wound to the abdomen requiring exploratory laparotomy 21 months earlier. Preoperative workup was unremarkable, but a hard, bone-like lesion was noted to encircle the base of the mesentery upon entering the abdomen, consistent with HO. The lesion was excised with close margins, and his hernia was repaired without incident.DISCUSSIONTraumatic HO describes the ossification of extra-skeletal tissue that specifically follows a traumatic event. It usually occurs adjacent to skeletal tissue, but has been occasionally described in the abdomen as well, usually in patients who suffer abdominal trauma. Overall the prognosis of HO is good, as it is considered a benign lesion with no malignant potential. However, the major morbidity associated with mesenteric HO is bowel obstruction.CONCLUSIONThe size, location, and symptoms related to our patient's mesenteric HO put him risk for obstruction in the future. As a result, the mass was surgically excised during his ventral hernia repair with good outcomes.

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Total heterotopic ossification of an acellular dermal matrix used for abdominal wall reconstruction

Cited by 5 publications

References 7 publications

Heterotopic Mesenteric Ossification With Trilineage Hematopoiesis

Heterotopic Mesenteric Ossification With Trilineage Hematopoiesis

Extensive Abdominal Wall Incisional Heterotopic Ossification Reconstructed with Component Separation and Strattice Inlay

Mesenteric calcification following abdominal stab wound

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