Total en bloc spondylectomy for spinal tumours: Technical aspects and surgical details

Delgado-López, Pedro David; Rodríguez-Salazar, Antonio; Martín-Velasco, Vicente; Castilla-Díez, José Manuel; Martín-Alonso, Javier; Galacho-Harriero, Ana; Gil‐Polo, Cecilia; Araús-Galdós, Elena

doi:10.1016/j.neucie.2016.07.002

Cited by 6 publications

(1 citation statement)

References 39 publications

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“…In case of spinal stenosis due to tumor the decompression of neural structures is reached via laminectomy and tumor debulking [13,29,43,46,47,50,[52][53][54][55] . According to Tomita et al [19] palliative anterior surgery with vertebral body replacement (VBR) [ Figures 1-3] can be recommended in patients with a life expectancy > 12 months [46,47,58,59] . Highly invasive surgical options like en-bloc spondylectomy in Tomita technique or vertebral column resection with a mandatory 360 reconstruction [ Figure 4] mark curative treatment options in case of solitary spinal metastases [46,47,58,59] .…”

Section: Therapeutic Options Regarding Spinal Metastasesmentioning

confidence: 99%

Operative treatment of metastatic breast cancer in the spine with regard to molecular phenotypes

Adler¹,

Pepke²,

Akbar³

2019

JCMT

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With more than one million new diseases per year breast cancer is the most common malignancy in women. Metastatic breast cancer remains an incurable disease and the spinal column is most likely affected by metastases. A significantly prolonged patient survival is the consequence of modern oncologic treatment options in the last decade. Surgical treatment of vertebral metastases has become an increasing focus for spine surgeons. With the turn of the millennium it was possible to classify breast cancer into four intrinsic phenotypes with various survival rates. Well known scoring systems help surgeons to evaluate the patient´s prognosis and to choose adequate treatment options. However, tumor entities are differentiated without regard to the molecular subtypes. In this article we describe surgical treatment options in metastatic lesions to the spine with regard to molecular phenotypes of breast cancer malignancy. It is crucial to correctly estimate the expected survival time to plan invasiveness of therapy regarding metastatic spine surgery.

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Section: Therapeutic Options Regarding Spinal Metastasesmentioning

confidence: 99%

Operative treatment of metastatic breast cancer in the spine with regard to molecular phenotypes

Adler¹,

Pepke²,

Akbar³

2019

JCMT

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Spinale Mammakarzinommetastasen aus Sicht der Wirbelsäulenchirurgie

et al. 2018

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Breast cancer is the most common malignancy affecting women and the spinal column is most likely affected by metastases. Modern oncologic treatment options have significantly prolonged survival times in the last decade. Therefore, treatment of vertebral metastases has been of special interest in spine surgery. Different scores are described to evaluate prognosis and to choose correct treatment strategies, which however only differentiate tumor entities and not specific tumor phenotypes. Breast cancer has been classified into five intrinsic subtypes with different survival rates since the turn of the millennium. The aim of this review was to describe molecular predictors of breast cancer malignancy and to better estimate expected survival times and invasiveness of therapies with regard to spinal metastases.

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Morphometrical evaluation of decompression obtained through corpectomy. Heading towards to posterior approaches

Delgado-Fernández

Simoes

García-Pallero

et al. 2019

Neurocirugía (English Edition)

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Total en bloc spondylectomy for spinal tumours: Technical aspects and surgical details

Cited by 6 publications

References 39 publications

Operative treatment of metastatic breast cancer in the spine with regard to molecular phenotypes

Operative treatment of metastatic breast cancer in the spine with regard to molecular phenotypes

Spinale Mammakarzinommetastasen aus Sicht der Wirbelsäulenchirurgie

Morphometrical evaluation of decompression obtained through corpectomy. Heading towards to posterior approaches

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