“…A well-accepted explanation for the development of CFS or even the relative contribution of the different possible mechanisms, however, remains elusive. CFS, a debilitating disease sharing many features with fibromyalgia 50 , CWP and similar idiopathic chronic fatigue syndromes, significantly impairs a patient's quality of life 51 , 52 , social 53 and emotional well being 54 , 55 , besides putting considerable economic strain on the community 56 . It is, therefore, imperative that a better understanding of the causation of CFS and related disorders is achieved to enable development of effective therapeutic options, which are currently lacking 57 .…”