Total cosine R‐to‐T for predicting ventricular arrhythmic and mortality outcomes: A systematic review and meta‐analysis

Tse, Gary; Gong, Mengqi; Wong, Cheuk Wai; Chan, Ckk; Georgopoulos, Stamatis; Chan, Yat Sun; Yan, Bryan P.; Li, Guangping; Whittaker, Paula; Ciobanu, Ana; Ali-Hasan-Al-Saegh, Sadeq; Wong, Sunny H.; Wu, William Ka Kei; Bazoukis, George; Λαμπρόπουλος, Κωνσταντίνος; Wong, Wing Tak; Tse, Lap Ah; Baranchuk, Adrián; Letsas, Κonstantinos P.; Liu, Tong

doi:10.1111/anec.12495

Cited by 12 publications

(9 citation statements)

References 22 publications

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“…The normal range in the general population based on the study was 72.2 ± 9.8 ms, and predictor value for the risk of ventricular arrhythmia was 99.8 ± 27.6. Meanwhile, the range in HFrEF population was 107 ± 22 ms, and predictor value for the risk of ventricular arrhythmia was 106.3 ± 8.4 [11,12]. The Tpe interval in our subjects was considered high compared to the general population but lower than HFrEF population.…”

Section: Discussionmentioning

confidence: 67%

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

et al. 2020

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Background: Ischemic cardiomyopathy is the most frequent etiology of heart failure with reduced ejection fraction (HFrEF) and a result of ventricular structural, functional and electrical remodeling. T peak to end (Tpe) interval is an electrocardiographic parameter that represents repolarization heterogeneity and had prognostic value for ventricular arrhythmia. Patients with ischemic cardiomyopathy face a significant burden of arrhythmias. Mechanical dispersion is a functional remodeling parameter that can be measured by time to peak longitudinal strain using speckle tracking echocardiography. This study aimed to assess the relationship between Tpe interval with time to peak longitudinal strain in ischemic cardiomyopathy patients. Methods: This study was conducted with an observational analytical cross-sectional design. Ischemic cardiomyopathy subjects were included at Dr. Hasan Sadikin General Hospital, Bandung, from August to October 2019. Tpe interval was measured manually with the tangential method. Time to peak longitudinal strain was measured using speckle tracking echocardiography. The correlation between Tpe interval and time to peak longitudinal strain was analyzed using Pearson correlation. Results: A total of 30 subjects were included in this study. The average age was 58 ± 8 years old, and the average left ventricular ejection fraction was 27±5.5%. The average of Tpe interval was 83.4 ± 7.62 ms, and the average time to peak longitudinal strain was 93.13 ± 34.51 ms. The Pearson correlation test showed a significant weak positive correlation (r = 0.386, 95% confidence interval: 0.029-0.743, P = 0.018) between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients. Conlucions: There was a significant weak positive correlation between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients.

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Section: Discussionmentioning

confidence: 67%

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

et al. 2020

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“…Уже 20 лет назад было показано, что у пациентов после инфаркта миокарда (ИМ) большое расхождение в пространстве векторов де-и реполяризации желудочков имело независимую прогностическую ценность в отношении внезапной сердечной смерти (ВСС) [2,3].…”

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Factors Associated with the Increase in Spatial and Frontal QRS-T Angles in Patients with Inferior Myocardial Infarction

et al. 2020

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Aim To identify clinical, echocardiographic, and angiographic factors related with an increase in the frontal QRS-T angle (fQRS-T) and the spatial QRS-T angle (sQRS-T) in patients with inferior myocardial infarction.Material and methods The study included 128 patients aged (median [25th percentile; 75th percentile]) 59.5 [51.5; 67.0] years diagnosed with inferior wall acute myocardial infarction. fQRS-T was calculated as a module of difference between the QRS axis and the Т axis in the frontal plane. sQRS-T was calculated by a synthesized vectorcardiogram as a spatial angle between the QRS and Т integral vectors.Results The fQRS-T for the group was 54.0 [18; 80] and sQRS-T was 80.1 [53; 110]. The correlation coefficient for fQRS-T and sQRS-T values was 0.42 (p<0.001). Both fQRS-T >80° and sQRS-T >110° compared to their lower values were associated with a higher frequency of history of postinfarction cardiosclerosis (44% and 12 %, respectively; p<0.05), a lower left ventricular ejection fraction (51 [47; 60]% at fQRS-T >80° and 55 [50; 60]% at fQRS-T <80° (p<0,05); 49 [44; 57]% at sQRS-T >110° and 57 [51; 60] % at sQRS-T <110° (p<0.01); more frequent development of acute heart failure (16 and 2 %, respectively; p<0.05); and early postinfarction angina (13 and 2 %, respectively; p<0.05). The increased fQRS-T was associated with a higher incidence of damage to the circumflex artery (45 and 20 %, respectively; p<0.05). The increased sQRS-T was associated with a history of arterial hypertension (97 and 76 %, respectively; p<0.05), chronic heart failure (22 and 3 %, respectively; p<0.05), chronic kidney disease (19 and 4 %, respectively; p<0.05), and a larger myocardial lesion (mean number of damaged segments by echocardiography was 3.8 [2; 6] at sQRS-T >110° and 2.6 [1; 4] at sQRS-T <110°; p<0.01). sQRS-T was significantly greater in multivascular damage (87 [68; 121]° than in one- or two-vascular damage (72 [51; 100]°; p<0.05). sQRS-T values were significantly lower with spontaneous reperfusion (66 [29; 79] than without spontaneous reperfusion (77 [55; 115]°; p<0.05).Conclusion In patients after inferior wall acute myocardial infarction, increases in fQRS-T and sQRS-T were associated with more severe damage of coronary vasculature, decreased left ventricular ejection fraction, and more severe course of disease.

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“…Dear Editor, My colleagues and I have read the review and meta-analysis of TCRT by Tse et al (2017) with substantial interest. Indeed, our team was the first to note the predictive value of increased spatial QRS-T angle (Zabel et al, 2000) and in this seminal clinical study, we used the TCRT technology that we previously developed (Acar, Yi, Hnatkova, & Malik, 1999).…”

Section: Shallow Meta Analysismentioning

confidence: 99%

Shallow meta analysis

Malik

2018

Noninvasive Electrocardiol

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Total cosine R‐to‐T for predicting ventricular arrhythmic and mortality outcomes: A systematic review and meta‐analysis

Cited by 12 publications

References 22 publications

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

Factors Associated with the Increase in Spatial and Frontal QRS-T Angles in Patients with Inferior Myocardial Infarction

Shallow meta analysis

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