Total and bioaccessible heavy metals in cabbage from major producing cities in Southwest China: health risk assessment and cytotoxicity

Li, Mengying; Qin, Yi-Shu; Wang, Chengchen; Wang, Kun; Deng, Zhihua; Xu, Wumei; Xiang, Ping; Lena, Q.

doi:10.1039/d1ra01440d

Cited by 24 publications

(7 citation statements)

References 53 publications

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“…The bioaccessibility of Cd in the current study (38%) was observed to be higher than the values reported by Yang et al (2012) for uncooked rice (16.61%), and remarkably lower than the 54% reported in shellfish (Amiard et al, 2008) and the 49-74% range reported in vegetables (Versantvoort et al, 2004). The Cd bioaccessibility percentage in this study was observed to be lower than the 87.3% reported for cabbage from major producing cities in Southwest China (Li et al, 2021) and the 71% reported by Hu et al (2013) in cabbages samples from Hong Kong. Similarly, Fu and Cui (2013) showed Cd bioaccessibility at 65% in cabbage.…”

Section: In Vitro Concentration Of Heavy Metals (Mg/kg) In Cbb Samples and Their Percentage Bioaccessibility (%)contrasting

confidence: 74%

Assessment of Anthropogenic Influence in Kurmi Cocoa Farmlands and Cocoa Beans using Heavy Metals as Indicators, and the In-vitro Bioaccessibility in Locally Produced Cocoa Based Beverages to Public Health

I.B¹,

S.P²,

S.T³

et al. 2021

IRJIET

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This study was conducted to assess the level of anthropogenic-influence across cocoa farmland soils, to cocoa beans and the locally produced cocoa-based beverages (CBB) from cocoa producing communities of Kurmi, Taraba State using heavy metals (Cr, Cu, Zn Pb, Cd, Mn, and Fe) as indicators. The results show Cr, Zn, and Pb in soil samples from Abong, Gidan Makeri, and Asha on the average detected to have values above the permissible limit (PL) set by the FAO/WHO. The further assessment shows only 23%, 39% and 4% of their total concentrations are from anthropogenic-related activities (Apn%) and of low ecological risk to the environment with potential ecological risk (Er) ˂40 and Ri≤10. The level of heavy metals in the cocoa beans samples analyzed were observed to be above the PL set by FAO/WHO. Compared to the values detected in the cocoa beans samples, the mean concentrations for Cr (6.25±1.88), Cu (7.78±2.87), Zn (19.73±7.19), Pb (18.10±6.59). Cd (4.78±2.07), Mn (8.26±4.92), and Fe (33.79±4.07) were observed to be significantly higher in the locally produced CBB samples. The in vitro digestion of the CBB samples shows mean bioaccessibility concentrations range from 0.67-3.38 mg/kg, with Fe, Cu, Cd, and Pb showing the highest mean concentration values of 3.38±2.64, 2.68±3.51, 1.84±1.82, and 1.65±1.27 mg/kg.The results revealed Cu and Cd with mean in vitro concentrations of 2.68±3.51, and 1.84±1.82 to be highly extracted in the gastrointestinal fluids showing a percent bioaccessibility of 34%and 39%. The estimated daily intake (EDI) of the metals were observed to be above the oral reference dose (RfD) values with average contributions rates (ACR) to RfD >100%.

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Section: In Vitro Concentration Of Heavy Metals (Mg/kg) In Cbb Samples and Their Percentage Bioaccessibility (%)contrasting

confidence: 74%

Assessment of Anthropogenic Influence in Kurmi Cocoa Farmlands and Cocoa Beans using Heavy Metals as Indicators, and the In-vitro Bioaccessibility in Locally Produced Cocoa Based Beverages to Public Health

I.B¹,

S.P²,

S.T³

et al. 2021

IRJIET

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“…Nevertheless, the impacts of bioaccessible metal(loid)s in vegetables on the morphology and viability of human gingival cells were not reported. Our previous study indicated gastric bioaccessible metals in cabbage did not cause the alteration of cell viability and morphology in human gastric adenocarcinoma cells ( 31 ). In this study, transformed cell morphologies were observed under all exposures excluded PAL , and cell viabilities were decreased across all exposures ( Figures 3A – F ).…”

Section: Resultsmentioning

confidence: 96%

The oral bioaccessibility and gingival cytotoxicity of metal(loid)s in wild vegetables from mining areas: Implication for human oral health

Gao¹,

Zong²,

Liu³

et al. 2022

Front. Nutr.

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BackgroundHeavy metal(loid)s are frequently detected in vegetables posing potential human health risks, especially for those grown around mining areas. However, the oral bioaccessibility and gingival cytotoxicity of heavy metals in wild vegetables remain unclear.MethodsIn this study, we assessed the total and bioaccessible Cr, As, Cd, Pb, and Ni in four wild vegetables from mining areas in Southwest China. In addition, the cytotoxicity and underlying mechanisms of vegetable saliva extracts on human gingival epithelial cells (HGEC) were studied.ResultsThe Plantago asiatica L. (PAL) showed the highest bioaccessible Cr, As, Cd, and Pb, while the greatest bioaccessible Ni was in Taraxacum mongolicum (TMM). The Pteridium aquilinum (PAM), Chenopodium album L. (CAL), and TMM extracts decreased cell viability, induced apoptosis, caused DNA damage, and disrupted associated gene expressions. However, PAL extracts which have the highest bioaccessible heavy metals did not present adverse effects on HGEC, which may be due to its inhibition of apoptosis by upregulating p53 and Bcl-2.ConclusionOur results indicated that polluted vegetable intake caused toxic effects on human gingiva. The heavy metals in vegetables were not positively related to human health risks. Collectively, both bioaccessibility and toxic data should be considered for accurate risk assessment.

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“…Cd in soil is mainly exposed through three ways: oral exposure, skin exposure, and respiratory exposure [17][18][19]. In this study, exposure routes，exposure levels, and the dose-response relationship of heavy metal Cd were comprehensively considered to determine the probability of harmful results, the acceptable level, and the uncertainty of evaluation results [20,21].…”

Section: Health Risk Assessment Modelmentioning

confidence: 99%

Characteristics and Health Risk Assessment of Cd in Soil around a Municipal Solid Waste Incineration Plant in Chengdu

Wei

Gong

Luo

2022

Mathematical Problems in Engineering

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Taking the Chengdu Municipal Solid Waste Incineration (MSWI) Plant in China as object, totally 100 ambient soil samples from 20 sampling points were taken for experiment. This paper analysed the characteristics of Cd in soil. By analyses, the distribution and health risk assessment were taken into consideration. The results demonstrated that the Cd value in soil in the surroundings of the MSWI plant was beyond the acceptable level according to standards (GB15618-2018). The risk assessment in this experiment showed that the carcinogenic and noncarcinogenic risks via inhalation exposure were in the accessible levels.

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Total and bioaccessible heavy metals in cabbage from major producing cities in Southwest China: health risk assessment and cytotoxicity

Abstract: We analyzed the total and bioaccessible concentrations of heavy metals in a popular vegetable cabbage (Brassica oleracea) from producing cities in Yunnan, Southwest China and assessed their health risk based on both bioaccessibility and cytotoxicity.

Cited by 24 publications

References 53 publications

Assessment of Anthropogenic Influence in Kurmi Cocoa Farmlands and Cocoa Beans using Heavy Metals as Indicators, and the In-vitro Bioaccessibility in Locally Produced Cocoa Based Beverages to Public Health

Assessment of Anthropogenic Influence in Kurmi Cocoa Farmlands and Cocoa Beans using Heavy Metals as Indicators, and the In-vitro Bioaccessibility in Locally Produced Cocoa Based Beverages to Public Health

The oral bioaccessibility and gingival cytotoxicity of metal(loid)s in wild vegetables from mining areas: Implication for human oral health

Characteristics and Health Risk Assessment of Cd in Soil around a Municipal Solid Waste Incineration Plant in Chengdu

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