Torticollis after low-dose aripiprazole administration in a Thai schizophrenia patient

Ittasakul, Pichai; Srivastava, Shalini; Hiranyatheb, Thanita; Ketter, Terence A.

doi:10.1016/j.ajp.2012.02.002

Cited by 3 publications

(2 citation statements)

References 11 publications

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“… 23) The first patient in the present study was male and had risk factors in terms of his age and gender, but the second was female and younger than most other dystonia cases. Similar to other cases, the present patients developed torticollis within the first 3 days of aripiprazole treatment, but in contrast to most cases of dystonia that occurred after aripiprazole doses of 10 mg/day and above, only the present cases and one other 22) developed dystonia after a dose of 5 mg/day.…”

Section: Discussionsupporting

confidence: 79%

“…19) There are reports of acute dystonia following treatment with aripiprazole at doses of 10 mg/day and above, 5 , 7 , 20 , 21) and aripiprazole-induced acute dystonia, particularly cases of torticollis, has been shown to be more frequent in young males. 22) Furthermore, male gender, younger age, cocaine abuse, a history of dystonia, and use of high-potency neuroleptics are known risk factors for the development of dystonia. 23) The first patient in the present study was male and had risk factors in terms of his age and gender, but the second was female and younger than most other dystonia cases.…”

Section: Discussionmentioning

confidence: 99%

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Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

Başay

Öztürk

2016

Clin Psychopharmacol Neurosci

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The present report describes the cases of a 17-year-old male patient and a 13-year-old female patient who developed acute dystonia following the administration of low-dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole-induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.

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Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

Başay

Öztürk

2016

Clin Psychopharmacol Neurosci

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Aripiprazole

2013

Reactions Weekly

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Aripiprazole Torticollis: case reportA 21-year-old man developed torticollis while receiving aripiprazole. He had been prescribed aripiprazole 10 mg/day [route not stated] for disorganised schizophrenia. He had previously experienced torticollis and neck rigidity while receiving other drugs for schizophrenia, and due to fear of side effects from aripiprazole he started at a dosage of 5 mg/day. Three days later, he developed torticollis. He received benztropine and the torticollis subsided.

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Acute Dystonia Versus Neuroleptic Malignant Syndrome Without Fever in an Eight-Year-Old Child

Sridaran

Nesbit

2017

Pediatr Emer Care

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Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal complication of the use of certain medications. It is being seen more often in the pediatric population because of the increasing use of both typical and atypical antipsychotics in children. Rapid recognition of NMS is important to emergency physicians because timely treatment can be life saving. Acute dystonia is also a well-known and more common adverse effect of certain types of antipsychotics, more commonly seen with the typical antipsychotics versus the atypical antipsychotics. We describe a case of a pediatric patient who developed an acute dystonic reaction versus NMS soon after starting aripiprazole. We compare this case with the other documented cases of acute dystonia and NMS after initiating aripiprazole in the pediatric population.

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Torticollis after low-dose aripiprazole administration in a Thai schizophrenia patient

Cited by 3 publications

References 11 publications

Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

Aripiprazole

Acute Dystonia Versus Neuroleptic Malignant Syndrome Without Fever in an Eight-Year-Old Child

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