Effective computation of resultants is a central problem in elimination theory and polynomial system solving. Commonly, we compute the resultant as a quotient of determinants of matrices and we say that there exists a determinantal formula when we can express it as a determinant of a matrix whose elements are the coefficients of the input polynomials. We study the resultant in the context of mixed multilinear polynomial systems, that is multilinear systems with polynomials having different supports, on which determinantal formulas were not known. We construct determinantal formulas for two kind of multilinear systems related to the Multiparameter Eigenvalue Problem (MEP): first, when the polynomials agree in all but one block of variables; second, when the polynomials are bilinear with different supports, related to a bipartite graph. We use the Weyman complex to construct Koszul-type determinantal formulas that generalize Sylvester-type formulas. We can use the matrices associated to these formulas to solve square systems without computing the resultant. The combination of the resultant matrices with the eigenvalue and eigenvector criterion for polynomial systems leads to a new approach for solving MEP.