Topological optimization of 3D printed bone analog with PEKK for surgical mandibular reconstruction

Cheng, Kang‐jie; Liu, Yunfeng; Wang, Russell; Zhang, Jian-xing; Jiang, Xianfeng; Dong, Xingtao; Xu, Xu

doi:10.1016/j.jmbbm.2020.103758

Cited by 44 publications

(38 citation statements)

References 26 publications

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“…Due to the inherent qualities of PEEK, it can be used to print parts for medical applications with better reliability [ 91 , 92 ]. The most popular areas that use PEEK in the medical industry are bone tissue engineering, orthopaedic implants, joint replacements, spinal implants, prosthesis systems and dentistry [ 93 , 94 , 95 , 96 ].…”

Section: Fused Deposition Modelling Of Thermoplastic Polymersmentioning

confidence: 99%

FDM-Based 3D Printing of Polymer and Associated Composite: A Review on Mechanical Properties, Defects and Treatments

2020

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Fused deposition modelling (FDM) is one of the fastest-growing additive manufacturing methods used in printing fibre-reinforced composites (FRC). The performances of the resulting printed parts are limited compared to those by other manufacturing methods due to their inherent defects. Hence, the effort to develop treatment methods to overcome these drawbacks has accelerated during the past few years. The main focus of this study is to review the impact of those defects on the mechanical performance of FRC and therefore to discuss the available treatment methods to eliminate or minimize them in order to enhance the functional properties of the printed parts. As FRC is a combination of polymer matrix material and continuous or short reinforcing fibres, this review will thoroughly discuss both thermoplastic polymers and FRCs printed via FDM technology, including the effect of printing parameters such as layer thickness, infill pattern, raster angle and fibre orientation. The most common defects on printed parts, in particular, the void formation, surface roughness and poor bonding between fibre and matrix, are explored. An inclusive discussion on the effectiveness of chemical, laser, heat and ultrasound treatments to minimize these drawbacks is provided by this review.

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Section: Fused Deposition Modelling Of Thermoplastic Polymersmentioning

confidence: 99%

FDM-Based 3D Printing of Polymer and Associated Composite: A Review on Mechanical Properties, Defects and Treatments

2020

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“…Teeth and the temporomandibular joint boundary condition are important parameters related to stress and strain distributions during occlusal loading [ 21 ]. Anisotropic properties of cortical and cancellous bone of the mandible and degree of mineralization as well as anatomic variations in the mandible are important information when constructing an accurate finite model [ 22 – 24 ]. We have taken into account those factors and integrated them into our physical and computational models.…”

Section: Discussionmentioning

confidence: 99%

“…The final FE model of the mandible consisted of 141,206 elements and 33,652 nodes. The material properties of the mandible were defined in Hounsfield units (HU) from CBCT images [ 17 , 22 ]. Figure 6 shows the locations and directions of masticatory muscle modeling including masseter, medial pterygoid, lateral inferior pterygoid and temporal muscle.…”

Section: Methodsmentioning

confidence: 99%

Experimental validation of finite element simulation of a new custom-designed fixation plate to treat mandibular angle fracture

Cheng

Liu

et al. 2021

BioMed Eng OnLine

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Background The objective of the study was to validate biomechanical characteristics of a 3D-printed, novel-designated fixation plate for treating mandibular angle fracture, and compare it with two commonly used fixation plates by finite element (FE) simulations and experimental testing. Methods A 3D virtual mandible was created from a patient’s CT images as the master model. A custom-designed plate and two commonly used fixation plates were reconstructed onto the master model for FE simulations. Modeling of angle fracture, simulation of muscles of mastication, and defining of boundary conditions were integrated into the theoretical model. Strain levels during different loading conditions were analyzed using a finite element method (FEM). For mechanical test design, samples of the virtual mandible with angle fracture and the custom-designed fixation plates were printed using selective laser sintering (SLS) and selective laser melting (SLM) printing methods. Experimental data were collected from a testing platform with attached strain gauges to the mandible and the plates at different 10 locations during mechanical tests. Simulation of muscle forces and temporomandibular joint conditions were built into the physical models to improve the accuracy of clinical conditions. The experimental vs the theoretical data collected at the 10 locations were compared, and the correlation coefficient was calculated. Results The results show that use of the novel-designated fixation plate has significant mechanical advantages compared to the two commonly used fixation plates. The results of measured strains at each location show a very high correlation between the physical model and the virtual mandible of their biomechanical behaviors under simulated occlusal loading conditions when treating angle fracture of the mandible. Conclusions Based on the results from our study, we validate the accuracy of our computational model which allows us to use it for future clinical applications under more sophisticated biomechanical simulations and testing.

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“…PSIs can be described as precisely fitted implants that allow for the restoration of sound anatomy and function generated through the use of patient-specific 3-D design and, typically, 3-D printing. For example, PSIs in craniomaxillofacial surgery include titanium implants that can be combined with autogenous bone grafts for reconstruction of mandibles with integrated dental implants, as well as polyether ether ketone ketone (PEKK) implants that have been developed for restoration/reconstruction of traumatic or genetic zygomatico-orbital and mandibular defects [ 110 ]. PSIs have also been used in orthopedic surgery for reconstruction of certain bony features following resection of tumors, as external fixators used in treating fractures, and in cervical spine restoration [ 111 – 114 ].…”

Section: Current Applications In Medicinementioning

confidence: 99%

Establishing a point-of-care additive manufacturing workflow for clinical use

Daoud

Pezzutti

Dolatowski

et al. 2021

Journal of Materials Research

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Graphical abstract Additive manufacturing, or 3-Dimensional (3-D) Printing, is built with technology that utilizes layering techniques to build 3-D structures. Today, its use in medicine includes tissue and organ engineering, creation of prosthetics, the manufacturing of anatomical models for preoperative planning, education with high-fidelity simulations, and the production of surgical guides. Traditionally, these 3-D prints have been manufactured by commercial vendors. However, there are various limitations in the adaptability of these vendors to program-specific needs. Therefore, the implementation of a point-of-care in-house 3-D modeling and printing workflow that allows for customization of 3-D model production is desired. In this manuscript, we detail the process of additive manufacturing within the scope of medicine, focusing on the individual components to create a centralized in-house point-of-care manufacturing workflow. Finally, we highlight a myriad of clinical examples to demonstrate the impact that additive manufacturing brings to the field of medicine.

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Topological optimization of 3D printed bone analog with PEKK for surgical mandibular reconstruction

Cited by 44 publications

References 26 publications

FDM-Based 3D Printing of Polymer and Associated Composite: A Review on Mechanical Properties, Defects and Treatments

FDM-Based 3D Printing of Polymer and Associated Composite: A Review on Mechanical Properties, Defects and Treatments

Experimental validation of finite element simulation of a new custom-designed fixation plate to treat mandibular angle fracture

Establishing a point-of-care additive manufacturing workflow for clinical use

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