TOPOLOGICAL INDICES & INDICATOR PARAMETERS USED IN PIPERDINE-4-CARBOXAMIDE DERIVATIVE CCR5 ANTAGONIST (TAK-220) WITH ANTI-HIV-1 ACTIVITY

Abstract

QSAR studies on Anti HIV-1 activity of Piperidine-4-Crboxamide Derivatives have been discussed. The topological, indicator parameters and biological activities were used. The predictive power of the model was examined using a CCR 5 a logIC 50.