Topical treatments for chronic plaque psoriasis

Mason, Anne; Mason, James; Cork, Michael J.; Dooley, Gordon; Edwards, Gladys

doi:10.1002/14651858.cd005028

Cited by 76 publications

(125 citation statements)

References 47 publications

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“…12,18 A recent Cochrane review of 131 randomized controlled trials, including 21,448 participants, evaluated the effectiveness, tolerability, and safety of topical treatments compared with placebo for chronic plaque psoriasis. 19 They concluded that most topical medications, specifically vitamin D derivatives and corticosteroid preparations, were significantly more effective than placebo. 19 However, despite the efficacy of topical treatments, in clinical practice topical treatments often fail to produce adequate improvement of the disease.…”

Section: Self-management With Topical Therapiesmentioning

confidence: 99%

“…19 They concluded that most topical medications, specifically vitamin D derivatives and corticosteroid preparations, were significantly more effective than placebo. 19 However, despite the efficacy of topical treatments, in clinical practice topical treatments often fail to produce adequate improvement of the disease. 7 This may be attributed in large part to poor adherence with treatment regimens.…”

Section: Self-management With Topical Therapiesmentioning

confidence: 99%

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Self-management in patients with psoriasis

Pathak¹,

Scott²,

West³

et al. 2014

PTT

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Psoriasis is a chronic inflammatory disorder effecting the skin and joints. Additionally, multiple comorbidities exist, including cardiovascular, metabolic, and psychiatric. The chronic nature of psoriasis is often frustrating for both patients and physicians alike. Many options for treatment exist, though successful disease management rests largely on patients through the application of topical corticosteroids, Vitamin D analogs, and calcineurin inhibitors, amongst others and the administration of systemic medications such as biologics and methotrexate. Phototherapy is another option that also requires active participation from the patient. Many barriers to effective self-management of psoriasis exist. Successful treatment requires the establishment of a strong doctor-patient relationship and patient empowerment in order to maximize adherence to a treatment regimen and improve outcomes. Improving patient adherence to treatment is necessary in effective self-management. Many tools exist to educate and empower patients, including online sources such as the National Psoriasis Foundation and online support group, Talk Psoriasis, amongst others. Effective self management is critical in decreasing the physical burden of psoriasis and mitigating its multiple physical, psychological, and social comorbidities, which include obesity, cardiovascular disease, alcohol dependence, depression, anxiety, and social anxiety.

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Section: Self-management With Topical Therapiesmentioning

confidence: 99%

Section: Self-management With Topical Therapiesmentioning

confidence: 99%

Self-management in patients with psoriasis

Pathak¹,

Scott²,

West³

et al. 2014

PTT

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“…The Cochrane Skin Group in UK published a review of topical therapies for chronic plaque psoriasis following examination of 131 studies (Mason et al, 2009). They concluded that vitamin D analogues showed similar efficacy as potent or very potent corticosteroids when used on the body, whereas topical corticosteroids proved the most effective treatment for scalp psoriasis.…”

Section: Guidances For Effective Management Of Psoriasismentioning

confidence: 99%

Topical Therapies for Psoriasis

Mitra¹,

Atillasoy²

2012

Psoriasis

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“…20,21 Acomete pessoas em qualquer faixa etária, com um maior predomínio na 2ª e 5ª décadas de vida, ao passo que a DA acomete preferencialmente crianças e sua prevalência é de aproximadamente 10%.…”

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“…20, 21 O paciente com psoríase geralmente apresenta outras morbidades associadas, como alcoolismo, depressão, obesidade, diabetes mellitus, hipertensão arterial, síndrome plurimetabólica, colite e artrite reumatoide, diferentemente da DA, na qual os pacientes frequentemente apresentam asma, rinite e atopias.…”

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Abordagem da dermatite atópica na infância pelo Médico de Família e Comunidade

Guilherme

Carvalho

Diniz

et al. 2014

Rev Bras Med Fam Comunidade

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Dermatite atópica (DA) é uma inflamação crônica e pruriginosa da pele, que acomete crianças nos primeiros anos de vida. Sua etiologia permanece pouco elucidada, mas sabe-se que ocorre uma disfunção da barreira cutânea que facilita a penetração de alérgenos/irritantes na epiderme, provocando reação inflamatória com predomínio de resposta Th2 em relação a Th1. O diagnóstico é clínico, podendo associar-se com a presença de história familiar e pregressa de atopias, como rinite e asma. A DA manifesta-se por meio de lesões eczematosas, pruriginosas, com presença de eritema, pápulas, vesículas e escamas. Os principais diagnósticos diferenciais são dermatite seborreica, dermatite de contato, psoríase e escabiose. O tratamento baseia-se na educação do paciente e de seus familiares, somado ao controle do prurido com anti-histamínicos e da inflamação com corticoides e inibidores da calcineurina. Devido à alta prevalência e impacto da DA na qualidade de vida de crianças, corrobora-se a importância do diagnóstico precoce e de uma abordagem individualizada.

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Topical treatments for chronic plaque psoriasis

Cited by 76 publications

References 47 publications

Self-management in patients with psoriasis

Self-management in patients with psoriasis

Topical Therapies for Psoriasis

Abordagem da dermatite atópica na infância pelo Médico de Família e Comunidade

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