Topical treatment of intertriginous candidal infection

Valenti, Lorenzo

doi:10.1111/j.1439-0507.2008.01617.x

Cited by 11 publications

(9 citation statements)

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“…As seen in previous case reports, a 2‐week treatment regimen with Travocort cream (containing the imidazole ISN 0.1% and the corticosteroid diflucortolone valerate) was effective in improving the clinical signs of tinea pedis and in alleviating the symptoms that most impacted the patient's QoL. Furthermore, the regimen was safe for use in patients with diabetes consistent with previous reports . ISN has a broad spectrum of antimicrobial activity against dermatophytes, pathogenic yeasts, filamentous fungi, moulds and gram‐positive bacteria .…”

Section: Discussionsupporting

confidence: 86%

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Friedrich¹

2013

Mycoses

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Undetected tinea pedis in a patient with diabetes can lead to serious bacterial infections with potentially serious consequences, such as foot amputations. Here we report on a 60-year-old patient with diabetes presenting with pain, severe pruritus, and malodour in the foot's interdigital area, and subsequently, diagnosed with inflammatory tinea pedis with bacterial superinfection. The patient was successfully treated with Travocort cream containing isoconazole nitrate 1% and diflucortolone valerate 0.1%; marked improvement occurred within 5 days.

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Section: Discussionsupporting

confidence: 86%

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Friedrich¹

2013

Mycoses

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“…In this patient, the intertrigo due to C. albicans led to discomfort in the form of severe pruritus. As seen in previous case reports, a 7‐day treatment regimen with Travocort completely alleviated the pruritus associated with candidal intertrigo and was well tolerated. ISN is an imidazole antifungal agent, and along with the corticosteroid DFV, is the active ingredient in the topical drug Travocort.…”

Section: Discussionsupporting

confidence: 79%

Rapid relief of intertrigo‐associated pruritus due to Candida albicans with isoconazole nitrate and diflucortolone valerate combination therapy

Veraldi

2013

Mycoses

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A 43-year-old male, with intertrigo due to Candida albicans located at the inguinal folds and accompanied by severe pruritus, was treated with topical 1% isoconazole nitrate and 0.1% diflucortolone valerate (2 applications/day for 7 days). An improvement of pruritus was reported 2 days after the beginning of the treatment. Skin lesions improved after 3 days of treatment. Complete remission of both skin lesions and pruritus was observed at day 7. No side effects were observed.

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“…Xerostomia, hyperhidrosis, occlusive wearings, occupational factors, use of corticosteroids or wide spectrum antibiotics, and immunosuppression including HIV infection may also increase the risk. 3 , 51 , 68 , 88 , 89…”

Section: Candidal Intertrigomentioning

confidence: 99%

Recurrent candidal intertrigo: challenges and solutions

Metin

Dilek

Bilgili

2018

CCID

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Intertrigo is a common inflammatory dermatosis of opposing skin surfaces that can be caused by a variety of infectious agents, most notably candida, under the effect of mechanical and environmental factors. Symptoms such as pain and itching significantly decrease quality of life, leading to high morbidity. A multitude of predisposing factors, particularly obesity, diabetes mellitus, and immunosuppressive conditions facilitate both the occurrence and recurrence of the disease. The diagnosis of candidal intertrigo is usually based on clinical appearance. However, a range of laboratory studies from simple tests to advanced methods can be carried out to confirm the diagnosis. Such tests are especially useful in treatment-resistant or recurrent cases for establishing a differential diagnosis. The first and key step of management is identification and correction of predisposing factors. Patients should be encouraged to lose weight, followed up properly after endocrinologic treatment and intestinal colonization or periorificial infections should be medically managed, especially in recurrent and resistant cases. Medical treatment of candidal intertrigo usually requires topical administration of nystatin and azole group antifungals. In this context, it is also possible to use magistral remedies safely and effectively. In case of predisposing immunosuppressive conditions or generalized infections, novel systemic agents with higher potency may be required.

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Topical treatment of intertriginous candidal infection

Cited by 11 publications

References 0 publications

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Inflammatory tinea pedis with bacterial superinfection effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy

Rapid relief of intertrigo‐associated pruritus due to Candida albicans with isoconazole nitrate and diflucortolone valerate combination therapy

Recurrent candidal intertrigo: challenges and solutions

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