Topical treatment of cutaneous larva migrans with ivermectin 1%

Cutaneous larva migrans imported from a tropical trip – Case report and literature review

“…Anti-histamines and topical corticosteroids are also used for symptomatic relief of pruritus. In some cases, topical treatment of CLM with ivermectin 1% cream appeared to be effective [19]. Kincaid et al [20] reported that short-term application of high-dose steroids may provide symptomatic relief of CLM, but prolonged therapy should be avoided.…”

New Approachment of Creeping Eruption Management

“…Case reports in the last 2 years, find several alternative options in the treatment of CLM. Case report from Andreas, et al who used krin ivermetin 1% once a day in male patients aged 20 years with the outcome of symptoms had disappeared within 3 days and only appeared post-inflammatory hyperpigmentation on 14 th day [7]. The second case report from Fischer, et al also uses ivermectin 1% cream twice a day in women aged 34 years with total remission results after 2 weeks of use [8].…”

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

“… When treating parasitic diseases, IVM proved to be more effective than albendazole (RR 1,79; IC 95%: 1,55 to 2,08), but similar to thiabendazole (RR 0,80; 95% IC: 0,59 a 1,09); however, the adverse events were fewer using IVM ( Henriquez-Camacho et al, 2016 ). Systematic reviews with meta-analysis: Henriquez-Camacho et al, 2016 Myiasis Oral administration with a single dose of 250 μg/kg Observational studies: Calvopina et al, 2020 Larva migrans Oral administration of a daily single dose of 200 μg/kg for two days Observational studies: Gerbig and Kempf, 2020 Pediculus humanus capitis Oral dose of 400 μg/kg on the first and eighth day, or 200 μg/kg with a repeated dose after 10 days Systematic review with meta-analysis: Jones and English 3rd., 2003 Randomized clinical trial: Chosidow et al, 2010 Rosacea (due to mite infestations, Demodex folliculorum) Topical 1% IVM demonstrated that ivermectin can control papulopustular rosacea and improve life quality. Systematic review and meta-analysis: Husein-ElAhmed and Steinhoff, 2020 Malaria There exists evidence of reduction in malaria indexes and sporozoites by 77% when mass IVM is used ( Alout et al, 2014 ).…”