Topical steroid damaged/dependent face (TSDF): An entity of cutaneous pharmacodependence

Lahiri, Koushik; Coondoo, Arijit

doi:10.4103/0019-5154.182417

Cited by 51 publications

(66 citation statements)

References 33 publications

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“…11 The incidence of TSDF was almost similar in studies done by Kaur Brar B et al and Chohan SN et al with 26% and 32.5% reported patients respectively. 9,10 This is a difficult to treat condition because of steroid addiction and less treatment options.…”

Section: Discussionsupporting

confidence: 65%

Topical corticosteroid abuse on face: a clinical study of 100 patients

Bains

2016

Int J Res Dermatol

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Background: Prolonged and uninterrupted use of topical corticosteroids on face is globally prevalant and this misuse has reached monstrous proportion in India. The topical corticosteroid abuse leads to various local adverse effects on face which are difficult to treat. The aim of this study was to ascertain the magnitude, demographics, cause and adverse effects of TC abuse on the face in the dermatology out-patient department.Methods: A total of 100 patients with history of topical corticosteroid abuse on face for a minimum period of one month were enrolled in this study.Results: In our study, majority of the patients were females (76%) and the most common age group was 21-30 years with 49% patients. The duration of application was <6 months (45%) in majority of patients. Most common topical corticosteroids abused were betamethasone valerate in 49% and clobetasol propionate in 40% cases.Conclusions: Topical corticosteroid abuse on face is quite common with varied presentation. There is need to take urgent remedial steps and increase awareness about this problem in general population.

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Section: Discussionsupporting

confidence: 65%

Topical corticosteroid abuse on face: a clinical study of 100 patients

Bains

2016

Int J Res Dermatol

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“…[14] TSDF is a new entity characterized by erythema or burning sensation or pruritus on attempted cessation of TCS application. [15] Persistent use of TCS can also lead to complications such as epidermal atrophy, degeneration of dermal structure with decrease collagen synthesis, rosacea, and susceptibility to superficial bacterial, viral and fungal infections. [14] Almost all these adverse effects were observed in our patients.…”

Section: Discussionmentioning

confidence: 99%

“…[14] TCS induced rosacea like dermatitis (TCIRD) is defined as a condition arising from prolonged use and the rebound phenomenon, which appears after discontinuation of TCS on the face. [15] Various other terms have been used by authors describing this entity such as topical steroid dependent face (TSDF), red face syndrome, steroid dermatitis resembling rosacea (SDRR) and steroid rosacea. [14] TSDF is a new entity characterized by erythema or burning sensation or pruritus on attempted cessation of TCS application.…”

Section: Discussionmentioning

confidence: 99%

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Chauhan¹

2017

jmscr

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“…In India annual sales figure of TC's was 209 million U.S. dollars. 4 Also inadequate policies regarding sale of medications by pharmacists further make the scenario more dismal and disturbing. The present study was undertaken at a tertiary centre of Jammu region to assess the magnitude of the problem, the demography of the abuse of steroids and various clinical adverse effects related to their misuse.…”

Section: Introductionmentioning

confidence: 99%

“…face (TSDF)" has recently been coined to encompass the various symptoms aggravated such as erythema or burning sensation on attempted cessation of topical steroid application. 4 These adverse events, including TSDF, have been further aggravated by inappropriate prescriptions and availability as over the counter drugs. Indian market is flooded with 18 different steroid molecules in various strengths and combinations.…”

Section: Introductionmentioning

confidence: 99%

Misuse of topical corticosteroids on facial skin. A study of 200 patients.

Sharma¹,

Abrol²,

Wani³

2017

J Dermatol Case Rep

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Background: Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions. Objective: The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin. Methods: A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study. This was a prospective study conducted in a tertiary care dermatology outpatient centre of the Jammu region. A detailed clinical history regarding topical corticosteroid use was taken and adverse effects analysed. Results: A total of 166 patients were women and 34 were men. The predominant age was 31-40 years. A total of 170 patients (85%) were in the age group of 21-50 years. Duration of application was over 1 month up to 3 years, daily. Betamethasone or clobetasol ointments were used in 75 patients (37.5%) and momatasone was used in 15 patients (7.5%). Indication for using steroids were: general / cosmetic purposes (72 patients; 36.0%), acne (59; 29.5%), hyperpigmentation (41; 20.5%), tinea (6; 3%), undiagnosed dermatoses (28; 14.0%). The use of corticosteroids was attributed to the advice of pharmacists (69; 34.5%), friends and relatives (61; 30.5%), cosmetologists (22; 11.0%), non-dermatology physicians (30; 15.0%) and dermatologists (18; 9%). Adverse effects included acneiform lesions, telengiectasias, dyspigmentation, hypertrichosis, perioral dermatitis and tinea incognito. A total of 89 (44.5%) patients fulfilled the criteria of "topical steroid dependent face". These patients reported erythema, burning and itching on stopping the application of topical corticosteroids. Conclusion:In most cases the use prolonged use of topical corticosteroids on facial skin was recommended by non-professional persons. The adverse events ranged from transient to permanent. The results of this study underline the indispensable role of dermatology specialists in diagnosing and treating cutaneous disorders. (J Dermatol Case Rep.

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Topical steroid damaged/dependent face (TSDF): An entity of cutaneous pharmacodependence

Cited by 51 publications

References 33 publications

Topical corticosteroid abuse on face: a clinical study of 100 patients

Topical corticosteroid abuse on face: a clinical study of 100 patients

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Misuse of topical corticosteroids on facial skin. A study of 200 patients.

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