Topical retinoids in the treatment of photoaging

Stefanaki, Christina; Stratigos, Alexander J.; Katsambas, Andreas

doi:10.1111/j.1473-2165.2005.40215.x

Cited by 27 publications

(23 citation statements)

References 49 publications

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“…Tretinoin (vitamin A derivative) is essential for the treatment of skin conditions including acne, eczema, psoriasis, photoaged skin, sunburns and other skin disorders (Elbaum, 1988;Brisaert et al, 2001;Stefanaki et al, 2005). Due to severe side effects when systemically used (Fenaux et al, 2001), tretinoin is almost topically used.…”

Section: Introductionmentioning

confidence: 99%

Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients

et al. 2015

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Topical tretinoin is the most commonly used retinoid for acne. However, its irritative potential on the applied area and the barrier properties of the stratum corneum limit its use. The objective of the present study was to formulate tretinoin liposomal gel to obtain a formula with lower skin irritation potential and greater clinical effect. A statistical 2 4 factorial design was adopted. Sixteen formulae prepared and were properly evaluated. A candidate formula (F13G) prepared with 0.025% tretinoin, phospholipid-cholesterol-dicetylphosphate (9:1:0.01) and incorporated in 1% carbopol gel was selected for skin irritation test. Clinical study was conducted on acne patients and compared to marketed product. All liposomes formulations were spherical in shape. The addition of cholesterol in the film hydration method significantly decreased the vesicle size, and increased the percentage of incorporation efficiency at (p50.05). The presence of dicetylphosphate significantly increased drug release but did not affect the percentage of incorporation efficiency and vesicle size. The results of the clinical study in acne patients revealed that F13G showed significantly higher efficacy when compared to marketed product (p50.05).

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Section: Introductionmentioning

confidence: 99%

Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients

et al. 2015

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“…Retinoids are therefore ideal for the treatment of photoaging. Numerous studies have confirmed the clinical efficacy of various retinoids [45][46][47][48][49][50] .…”

Section: Retinoidsmentioning

confidence: 99%

Untitled

2012

IJPSR

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Traditional remedies and preparation used for the treatment of skin, or the folk preparations used for healing skin diseases are known to be as Cosmeceuticals and cosmetics. The desire of gook looking and to be beautiful gave a huge market for the cosmetics. This is not a new tradition for human to look good; it has been a long ancient follow through for both the sexes to be presentable by beauty. For now, the desire of both the sexes to look younger than there age, to be fare and charming have directly increased the demand of herbal cosmetics as well as of the Cosmeceuticals in the market. The herbal formulations have been the first choice of the customers. For the reason of being less side effective and thought to be more potent than the synthetic formulations. There has been a long use of turmeric and sandalwood to be applied of face for fairness and freshness. As like many other herbs are used in daily life to be called as cosmetics and the preparation from them to be called as Cosmeceuticals. The above article is an effort to describe clearly both the terms and the relation between them.

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“…Topical applications of these agents are indicated for dermatological conditions with increased cell turnover such as psoriasis [23] and inflammatory skin disorders such as acne [24] . Retinoids are also ideal for treating photoaging and skin wrinkles [25,26] . The inhibition of tyrosinase action provides an effective environment for reducing doi: 10.18282/jsd.v1.i2.…”

Section: Retinoidsmentioning

confidence: 99%

Treatment modalities for hyperpigmented skin lesions: A brief overview

Khoo¹,

Halim

2016

J Surg Dermatol

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Skin hyperpigmentation involves a broad range of skin conditions, including epidermal pigmented lesions, dermal pigmented lesions, and mixed pigmented lesions. Treatment includes various modalities such as brightening cream, chemical peeling, and laser therapy. Responses to various treatment modalities can be quite varied depending on the type of treatment and the degree of pigmentation. Sometimes a lesion can lighten or even partially disappear, while other lesions may recur. This paper provides a brief overview of treatment modalities available for hyperpigmented skin lesions including the importance of photoprotection, various types of brightening creams, suitable types of chemical peels, specific laser therapies targeted for skin hyperpigmentation, and surgery.

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Topical retinoids in the treatment of photoaging

Cited by 27 publications

References 49 publications

Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients

Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients

Untitled

Treatment modalities for hyperpigmented skin lesions: A brief overview

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