2007
DOI: 10.1002/14651858.cd003163.pub4
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Topical nasal steroids for intermittent and persistent allergic rhinitis in children

Abstract: Background Allergic rhinitis is a very common chronic illness a ecting 10% to 40% of children worldwide. There has been a significant increase in prevalence among children over the last two decades and this increase has been accompanied by a parallel increase in comorbid illnesses such as asthma. Objectives To evaluate the therapeutic e ectiveness and adverse event profiles of topical nasal steroids for intermittent and persistent allergic rhinitis in children.

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Cited by 37 publications
(13 citation statements)
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“…The articles included epidemiologic studies in the general population (cross-sectional [16][17][18][19][20][21][22][23] and cohort 24 ), observational studies among primary care physicians and specialists, and interventional studies, including 5 large-scale, double-blind, placebocontrolled trials. [25][26][27][28][29] Three Cochrane Collaboration reviews using the ARIA classification have been finalized, [30][31][32] and others are pending.…”
Section: Scientific Publications Using the Aria Classificationmentioning
confidence: 99%
“…The articles included epidemiologic studies in the general population (cross-sectional [16][17][18][19][20][21][22][23] and cohort 24 ), observational studies among primary care physicians and specialists, and interventional studies, including 5 large-scale, double-blind, placebocontrolled trials. [25][26][27][28][29] Three Cochrane Collaboration reviews using the ARIA classification have been finalized, [30][31][32] and others are pending.…”
Section: Scientific Publications Using the Aria Classificationmentioning
confidence: 99%
“…15 A systematic review of nasal corticosteroids in children with allergic rhinoconjunctivitis applied such strict selection criteria that only three small old studies with methodological flaws were included. 16 The most common local side effect is epistaxis (nose bleeds), which occurs in 17-23% of patients, although it is also common (10-15%) in patients treated with placebo in clinical trials. 17 Therefore, local trauma caused by the nozzle of the nose spray probably causes epistaxis in many cases, rather than the drug itself.…”
Section: Intranasal Glucocorticosteroidsmentioning
confidence: 99%
“…In children, they should be used at the lowest dose that controls symptoms, particularly when used concurrently with other inhaled or intranasal steroids. 17 Occasionally, intranasal steroids may be associated with dryness, crusting, or slight bleeding, which if recurrent may necessitate withdrawal of treatment.…”
Section: Swabs Smears and Biopsiesmentioning
confidence: 99%