Topical mitomycin C application post endoscopic removal of antrochoanal polyp

Abstract

Objective Assessment the effect of topical application of mitomycin‐C (MMC) after endoscopic removal of antrochoanal polyp (ACP) on its recurrence rate. Methods This prospective study was done on patients with ACP. Endoscopic nasal surgery has been done to remove the polyp after wide middle meatal antrostomy. The patients were categorized into two groups. In MMC group, after endoscopic ACP removal, MMC on a piece of cotton was topically applied inside the maxillary antrum in the suspected site of ACP origin. A second group was used as a control group without MMC application. Results The study included on 40 patients; 20 patients in each group. Topical MMA application was easily performed. No granulation, crust, infection, or bleeding was reported in all cases of both groups. Recurrent polyp was not reported in MMC group, while recurrent polyp was detected in four cases (20%) in control group without MMA application with statistically significant difference (P = .035). Conclusion Topical MMC application inside the maxillary sinus after endoscopic removal of the ACP is safe, easy, and effective. Level of evidence 2c.

Comparison of conventional and extended middle meatal antrostomy for the treatment of antrochoanal polyps

“…El-Sharkawy [ 8 ] reported that 38.9% were located in the posterior and lateral walls, 36.1% in the medial wall, and 8.3% in the inferior wall. Some scholars found that 7/12 were in the inferolateral wall, while 2/12 were in the inferomedial and superomedial walls, and 1/12 were in the margin of the ostium [ 9 ]. In this study, the ACP was located in the inferomedial wall in 35.79%, in the inferolateral wall in 23.16%, in the inferior wall in 14.74%, and in the anterior wall in 10.53%.…”