Topical hydrogen peroxide solution 40%in the treatment of genital warts

Abstract

Background; The visible result of a human papillomavirus (HPV) infection caused by one or more of the roughly 100 known strains is genital warts. The most prevalent STD in the world is HPV, and infections with it are strongly linked to major morbidity and death. Numerous malignancies and lesions of the mucosa and epithelium are caused by HPV. Women under the age of 25 are most typically affected by HPV infections, Aim and objectives; to evaluate the efficacy and safety of topical hydrogen peroxide solution 40% in treatment of genital warts, Subjects and methods; this study was a randomized controlled trial that was conducted on 52 patients attending the Dermatology outpatient clinic at Damietta Faculty of Medicine, Al-Azhar University. The selected subjects were divided into 26 patients treated with topical H2O2 as Hydrogen peroxide group and 26 patients treated with saline as control group. Result; There is statistically significant positive correlation between Size of wart after ttt and number of wart after ttt. There is statistically significant reduction in the number of warts with decrease its number after ttt. However, there is no statistically significant correlation between the size and number of warts after ttt with other clinical variables, Conclusion; One possible course of therapy for genital warts may be hydrogen peroxide solution, particularly the 40% concentration. As a novel topical therapy for genital warts, it is very efficient, secure, affordable, and simple to apply,