Topical corticosteroid-induced iatrogenic cushing syndrome in an infant; a case report with literature review

Drug-induced Steatohepatitis Caused by Long-term Use of Topical Steroids for Atopic Dermatitis: A Case Report

“…Children are more susceptible than adults to such effects due to their greater body surface-to-weight ratio (8,9). While systemic side effects of TCs are rare, there are reports of hypothalamic-pituitary-adrenal axis suppression and adrenal insufficiency caused by TCs (1,2,12). A study by Güven reviewed 14 children, ranging from 0.19 to 11.89 years old, who were diagnosed with iatrogenic Cushing's syndrome due to hypothalamic-pituitary-adrenal axis suppression caused by potent GCs administered orally and topically (1).…”

Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes

“…Only a few cases of new-onset DM following TStreatment have been published [22][23][24][25]. Kahara et al reported a patient receiving class VII (lowest potency) TS applied to the oral mucosa for several months to treat lichen planus.…”

“…Significant associations between TS and the risk of T2D have been shown in previous, retrospective studies [ 19 – 21 ]. The magnitude of this risk remains uncertain, and only a few case reports have described the use of TS resulting in overt T2D [ 17 , 22 – 25 ].…”

Simultaneous pituitary and adrenal adenomas in a patient with non ACTH dependent Cushing syndrome; a case report with literature review

“…Cushing syndrome (CS) is a collection of clinical manifestations caused by an excess of glucocorticoids [1] . CS is a rare disorder with a variety of underlying etiologies that can be exogenous due to continuous corticosteroid therapy for any underlying inflammatory illness or endogenous due to either adrenocorticotropic hormone (ACTH)-dependent or ACTH-independent [2] , [3] .…”