Topical Chemotherapeutic Effect of Thymoquinone, Epigallocatechin-3-gallate, and Curcumin on Chemically Induced Oral Epithelial Dysplasia in Hamsters.
Merhan Elmansy,
Mona Shata,
Randa El-sherbiny
Abstract:This study aimed to compare the effects of Thymoquinone (TQ), Epigallocatechin gallate (EGCG) and Curcumin (CUR) on the inhibition of progression of oral premalignant lesions to invasive carcinoma through detection of PCNA and Caspase 3 expression. Thirty Syrian golden hamsters were divided into 5 groups (n=6). G.A: no treatment was given. The remaining hamsters were painted three times per week for six weeks with 0.5% DMBA. Then, they were subdivided into: G.B 1: did not receive any treatment till 12 th week.… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.