Topical aspects of the use of phytopreparations in acute infectious and inflammatory diseases of the upper respiratory tract

Abstract

Acute infectious and inflammatory diseases of the upper respiratory tract today belong to the category of the most common pathological conditions. Most often they occur in the form of acute nasopharyngitis, acute rhinosinusitis and acute laryngitis, the clinical of which consists of such symptoms as general weakness, hyperthermia, nasal blockage and nasal discharge, dysosmia, pain and tickling in the throat, cough, dysphonia. The need to select a safe and effective mucoactive therapy justifies the use of the phytopreparation in this pathology, the main active ingredient of which is an extract of ivy leaves. Also in the composition of the drug includes anise oil, peppermint oil, eucalyptus oil and levomenthol. The mechanism of action of is associated with α-hederin contained in ivy leaves. This substance, binding to the beta-adrenoreceptors of the bronchi, causes relaxation of their smooth muscles. In addition, thanks to the saponins contained in the leaves of common ivy, a mucolytic and expectorant effect is achieved. Literature data show that ivy leaf preparations significantly reduce the severity of acute respiratory infections of the upper respiratory tract. Virtually none of the patients had severe side effects. Allergic reactions were recorded in less than 0.5% of cases, with no mention of a severe allergic reaction of the anaphylaxis type. Thus, the drug of plant origin in the form of drops can be successfully used in patients with symptoms of acute respiratory diseases.

Changes in local immune status in tonsillopharyngitis under pathogenic therapy with the BNO 1030 extract: a randomized, comparative, parallel-group, single-center study

“…Modern medicine has an abundance of pharmacological agents used for treatment of inflammatory processes in oropharynx, while at the same time, in the case of an acute pharyngitis on the out-patient stage, antibiotics are prescribed in 65-85% of cases (of which parenterally -more than 40%). In hospitals 98% of TP cases (parenterally -90%) are treated with antibiotics, although, because of its viral etiology, this is neither justified nor expedient [6].…”