Topical anaesthesia before nasendoscopy: a randomized controlled trial of co‐phenylcaine compared with lignocaine

Abstract

Nasendoscopy can be performed with minimal discomfort after the administration of either co-phenylcaine or lignocaine 5% sprays. The vasoconstricting action of co-phenylcaine increases the ease of passage of the endoscope and quality of the view obtained by the endoscopist.

Treatment of dysmenorrhoea with a new TENS device (OVA)

“…Is the reduction in pain scores also clinically significant? In the literature, a change of 0.9 -1.5 (or 2) on a 0 -10 point scale or a 10% difference between groups is usually considered to be clinically significant (Kelly 1998;Abbot et al 2001;Douglas et al 2006;Cruise et al 2006; Appell et al 2006). In our study, the reduction was 1.55 VAS points, corresponding to 23%, indicating that our results are clinically significant.…”

Assessing the safety and efficacy of drugs used in preparing the nose for diagnostic and therapeutic procedures: a systematic review

“…In contrast, other studies have investigated the use of a sole vasoconstrictor or decongestant. Xylometazoline is a cheap decongestant with few side‐effects, although not as efficacious as anaesthetic alone, and can be used to improve tolerance and ease of procedure by widening the nasal aperture …”

A double‐blind randomised controlled trial assessing the efficacy of topical lidocaine in extended flexible endoscopic nasal examinations

“…In addition to this, it is unclear if the results would be similar if a rigid endoscopic examination was performed. Previous studies assessing the rigid endoscopic examination demonstrate similar levels of discomfort compared with flexible endoscopic nasal examinations 15–17 . However, these studies assessing the rigid endoscope contain many of the confounding variables present in studies assessing flexible examinations.…”