Topical 3-bromopyruvate is a novel targeted therapy for melanoma in a preclinical model

Yamada, Masayuki; Kagaya, Makoto; Noguchi, Natsuko; Ueki, Shigeharu; Hasunuma, Naoko; Osada, Shigehiro; Manabe, Motomu

doi:10.1016/j.jdermsci.2018.08.009

Journal of Dermatological Science

2018

DOI: 10.1016/j.jdermsci.2018.08.009

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Topical 3-bromopyruvate is a novel targeted therapy for melanoma in a preclinical model

Masayuki Yamada¹,

Makoto Kagaya²,

Natsuko Noguchi³

et al.

Abstract: We have now proposed that a targeted therapy with topical 3BP is an innovative strategy for adjuvant chemotherapy of technically or medically unresectable melanoma and possibly other skin cancers.

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2020

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Topical 3-bromopyruvate is a novel targeted therapy for melanoma in a preclinical model

Abstract: We have now proposed that a targeted therapy with topical 3BP is an innovative strategy for adjuvant chemotherapy of technically or medically unresectable melanoma and possibly other skin cancers.

Cited by 1 publication

References 38 publications

3-Bromopyruvate inhibits the malignant phenotype of malignantly transformed macrophages and dendritic cells induced by glioma stem cells in the glioma microenvironment via miR-449a/MCT1

3-Bromopyruvate inhibits the malignant phenotype of malignantly transformed macrophages and dendritic cells induced by glioma stem cells in the glioma microenvironment via miR-449a/MCT1

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