In modern manufacturing, the prediction of the remaining useful life (RUL) of computer numerical control (CNC) milling cutters is crucial for improving production efficiency and product quality. This study proposes a hybrid CNN-LSTM-Attention-PSA model that combines convolutional neural networks (CNN), long short-term memory (LSTM) networks, and attention mechanisms to predict the RUL of CNC milling cutters. The model integrates cutting force, vibration, and current signals for multi-channel feature extraction during cutter wear. The model’s hyperparameters are optimized using a PID-based search algorithm (PSA), and comparative experiments were conducted with different predictive models. The experimental results demonstrate the proposed model’s superior performance compared to CNN, LSTM, and hybrid CNN-LSTM models, achieving an R2 score of 99.42% and reducing MAE, RMSE, and MAPE by significant margins. The results validate that the proposed method has significant reference and practical value for RUL prediction research of CNC milling cutters.