Too Early to Put Down RDW for Discriminating Iron Deficiency and Thalassemia

Bessman, J. David; Gilmer, P. Ridgway; Gardner, Frank H.

doi:10.1093/ajcp/86.5.693

Cited by 11 publications

(3 citation statements)

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“…1 RDW levels have been already used to differentiate the types of anemia. 16 In fact, high values indicate more difference in the size of RBCs which could be a sign of iron deficiency anemia in association with low MCV 17 and converse relationship between RDW, Hb, and MCV is a known fact. 9,18 In this study, we also found the similar relationship.…”

Section: Discussionmentioning

confidence: 99%

Effect of Baseline Red Blood Cell Distribution Width on Short- and Intermediate-term Mortality of Patients Under Primary Percutaneous Coronary Intervention

Bozorgi

Khaki

Mortazavi³

et al. 2016

Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine

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Section: Discussionmentioning

confidence: 99%

Effect of Baseline Red Blood Cell Distribution Width on Short- and Intermediate-term Mortality of Patients Under Primary Percutaneous Coronary Intervention

Bozorgi

Khaki

Mortazavi³

et al. 2016

Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine

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“…Elevated RDW help health care providers in the diagnosis of early nutritional deficiency such as iron, vitamin B 12 or folat as it becomes elevated earlier than other RBC parameters (6). In addition, RDW helps clinicians to differentiate between iron deficiency and heterozygous thalassemia, and also between megaloblastic anemia such as vitamin B 12 or folat deficiency anemia together with other causes of macrocytosis (7). Thus patients with anemia were excluded in our study.…”

Section: Discussionmentioning

confidence: 99%

Investigation the Effect of Hypothyroidism on Hematological Parameters Hi̇poti̇roi̇di̇ni̇n Hematoloji̇k Parametreler Üzeri̇ne Etki̇si̇ni̇n İncelenmesi̇

Olt

Selçuk²,

Tutak³

et al. 2016

Mustafa Kemal Üniv Tıp Derg

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Aim: To investigate impact of the hypothyroidism on hematological parameters.Material and Method: Twenty patients with hypothyroidism and twenty two healthy subjects were enrolled in this study between February 2015 and July 2015. We collected clinical and laboratory data of patients with hypothyroidism and randomized healthy subject's from the Adıyaman University Medical Faculty Hospital records retrospectively. The patients with anemia, rheumatic diseases, chronic kidney diseases, chronic liver diseases, chronic obstructive pulmonary disease, chronic heart diseases, inflammatory bowel diseases, malignancy and acute infections were excluded from the study. Patients were divided into two groups; hypothyroid group and healthy group. TSH values were increased in all of the hypothyroid patients. We compared hematological parameters consist of hemoglobin, platelet count, white blood cell (WBC), red cell distribution width (RDW) and mean platelet volume (MPV) between the two groups.Results: 70% of patients with hypothyroidism were female and 30% of patients were male. Mean age of patients with hypothyroidism were 44,8±13,4. 72,7% of healthy subjects were female and 27,3% of healthy subjects were male. Mean age of healthy subjects was 31±14,6. In the result with Independent sample T test increased RDW-CV values was significantly associated with hypothyroidism (P value =0.01). The other hematological parameters weren't different between the groups (P value >0.05). Conclusion:The present study demonstrated that increased RDW values was associated with hypothyroidism.

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“…Similarly the utilization of the dynamic changes in red blood cells (RBC) counts and their indices had been ignored in asthma classification. It is reasonable to assume that early stages of asthma elicit hypoxic stimulus that inducts the release of RBC whereas late stages of asthma represent sustained hypoxia which leads to tissue damage and ischemia which in turn impact the sources (organs) of RBC productions [28,35,9]. Altogether there is a need to model the relationships of the dynamic changes in blood cell counts and the morphological changes in CXR, as clinical outcome for treatment and follow up of asthma in primary care clinic.…”

Section: Introductionmentioning

confidence: 99%

Reliable quantitative score for grading chest X-ray using the dynamic of blood cell count in adult asthma

Haffor¹,

Dahan

Ismaeel³

2015

Egyptian Journal of Chest Diseases and Tuberculosis

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The purpose of the present study was to rate the level of spread of asthma-induced bronchial morphological changes on chest X-ray (CXR), using the modified Shwachman-Kulczycki (S-K) rating scale as predicted by the dynamic of blood cell count (CBC). A sample of 40 asthma patients' records was classified into 4 groups based on their clinical presentations and frequency of their visits to the hospital; Group-1 62 visits per week with reversible symptoms, Group-2 P2 visits per week with irreversible symptoms, Group-3: P3-4 visits per week with irreversible symptoms; Group-4: patients with severe shortness of breath in whom SaO 2 was threatening, hence were admitted as inpatients. Patients' CXR were scored based on the modified Shwachman-Kulczycki (S-K) scale rating. Blood analysis showed that RBC and their indices (HCT, HGB, MCH, RDW) were highest in group-2. White blood cells and their derivatives (NEU, EOS and LYM) were highest in group 4. CXR for group-2 showed bilateral increased bronchovascular markings but normal both lung fields and ruled out for costo-phrenic angles type of fever. Chest X-ray for group-3 showed hyperinflation, perihilar marking associated with bronchial thickening and unfolding aorta. In patients in group-4 development of broncho-pneumonic infiltration type of SOB and some evidence of bronchial edema with significant (p < 0.05) elevation in WBC were observed. The regression of S-K score on the dynamic of some CBC parameters was significant (p < 0.05). The best subsets that describe the model were:S-K ¼ 14:242 þ b1 NEUðÀ1:28Þ þ b2 EOSðÀ10:929Þ þ b3 HCTð0:577Þ þ b4 HGBðÀ:898Þ þ b5 RDWð0:546Þ þ b6 RBCðÀ1:966Þ þ e

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Too Early to Put Down RDW for Discriminating Iron Deficiency and Thalassemia

Cited by 11 publications

References 0 publications

Effect of Baseline Red Blood Cell Distribution Width on Short- and Intermediate-term Mortality of Patients Under Primary Percutaneous Coronary Intervention

Effect of Baseline Red Blood Cell Distribution Width on Short- and Intermediate-term Mortality of Patients Under Primary Percutaneous Coronary Intervention

Investigation the Effect of Hypothyroidism on Hematological Parameters Hi̇poti̇roi̇di̇ni̇n Hematoloji̇k Parametreler Üzeri̇ne Etki̇si̇ni̇n İncelenmesi̇

Reliable quantitative score for grading chest X-ray using the dynamic of blood cell count in adult asthma

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