Tonic serotonergic control of ingestive behaviours in the pigeon (Columba livia): The role of the arcopallium

Campanella, Luciane Coutinho Azevedo; Silva, Amanda Alcaraz da; Gellert, Dayane Stephany; Parreira, Caroline; Ramos, Mayara Caldas; Paschoalini, Marta Aparecida; Marino–Neto, José

doi:10.1016/j.bbr.2009.07.017

Cited by 16 publications

(10 citation statements)

References 91 publications

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“…These effects seemed to be regionally specific because Metergoline and GR46611 injections into the arcopallium mediale (AM) failed to affect those behaviors. In line with this, we found only low 5-HT 1A densities in TnA and AI, supporting the view that transmission through 5-HT 1A receptors in those regions plays no, or only a minor role in ingestive behavior (Campanella et al, 2009). However, our findings are in contrast to those of the mammalian amygdaloid nuclei, which contain high or intermediate 5-HT 1A receptor concentrations (Hall et al, 1997;Yilmazer-Hanke et al, 2003;Palchaudhuri and Flügge, 2005;Perez-Garcia and Meneses, 2008).…”

Section: Discussionsupporting

confidence: 74%

“…A dense 5-HT innervation was found for limbic structures like the TnA, the parahippocampal area (APH), hippocampus (HP), and area septalis in pigeons, chicken, and quails (Yamada et al, 1985;Cozzi et al, 1991;Challet et al, 1996). Recently it was shown that injections of the 5-HT 1/2/7 receptor antagonist Metergoline and the 5-HT 1B/1D agonist GR46611 into TnA induced hypophagic responses, whereas the same treatment in the arcopallium intermedium (AI) resulted in a selective increase in water intake (Campanella et al, 2009). These effects seemed to be regionally specific because Metergoline and GR46611 injections into the arcopallium mediale (AM) failed to affect those behaviors.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, the role of 5-HT 1A receptor signaling in behavioral outcome and cognitive functions is less investigated in the avian brain compared with mammals. Only a few studies suggest a role for this receptor type in ingestive behavior, circadian rhythm, sleep (Tejada et al, 2011;Fuchs et al, 2006;Garau et al, 2006;Da Silva et al, 2007;Campanella et al, 2009;Dos Santos et al, 2009), and impulsive reactions (Wolff and Leander, 2000). It was demonstrated that 5-HT modulates executive function during working memory in pigeons (Karakuyu et al, 2007) and possibly plays a role in visual attention switching (Miceli et al, 1999(Miceli et al, , 2002 and ingestive behavior (Güntürkün et al, 1989).…”

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confidence: 99%

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Serotonin 5-HT1A receptor binding sites in the brain of the pigeon (Columba livia)

et al. 2012

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Serotonin (5-HT) is a modulatory neurotransmitter that is involved in a variety of physiological and behavioral functions. In mammals, dysfunction of the serotonergic system has been linked to various diseases such as depression, schizophrenia, Alzheimer's disease, and eating disorders (Müller et al., 2007;Michelsen et al., 2008;Remington, 2008;Terry et al., 2008;Akimova et al., 2009;Polter and Li, 2010). In addition, growing evidence found in many species indicates that 5-HT modulates learning and memory (Jacobs and Azmitia, 1992;Winsauer et al., 1996; Meneses, 1999;Clarke et al., 2004; Meneses and PerezGarcia, 2007;Müller et al., 2007;Bert et al., 2008;Gasbarri et al., 2008;González-Burgos and Feria-Velasco, 2008;Sitaraman et al., 2008;Sambeth et al., 2009;Bari et al., 2010).Serotonin binds to multiple receptors (Hoyer et al., 2002;Green, 2006), which are widely distributed throughout the brain (Chalmers and Watson, 1991;Baumgarten and Grozdanovic, 1995;Barnes and Sharp, 1999;Riad et al., 2000). One of the most prominent is the 5-HT 1A receptor, which was first cloned and described by Fargin et al. (1988). The 5-HT 1A receptor belongs to the G protein coupled receptor superfamily and binds to a Gi/o protein (Innis and Aghajanian, 1987;Polter and Li, 2010). It displays a high affinity for 5-HT and occurs both pre-and postsynaptically (Hall et al., 1985;van Wijngaarden et al., 1990;Riad et al., 2000). As somatodendritic autoreceptors, 5-HT 1A receptors modulate the activity of 5-HT neurons, whereas they modify neuronal activity in terminal areas as postsynaptic receptors (Müller et al., 2007).The distribution of 5-HT 1A receptors in the brain has been investigated by several methods in rodents, nonhuman primates, and humans. Thereby, a high correlation between receptor binding with [3H]-8-hydroxy-2-(di-n-propylamino)tetralin ([ 3 H]-8-OH-DPAT) and 5-HT 1A mRNA densities has been shown (Chalmers and Watson, 1991;Pompeiano et al., 1992). High 5-HT 1A receptor densities were detected in the dorsal and median raphe nuclei and in areas of the limbic system such as the hippocampus, the lateral septum, the amygdala, as well as the entorhinal and cingulate cortices Zilles et al., 1985Zilles et al., , 2000Palacios et al., 1990;Yilmazer-Hanke et al., 2003). Moderate binding was detected in the olfactory bulb, the thalamus, hypothalamus, and several brain stem nuclei as well as neocortical areas. Low levels, or no binding, were reported in the basal ganglia and cerebellum (Gozlan et al., 1983;Marcinkiewicz et al., 1984;Zilles et al., 1985Zilles et al., , 2000Hall et al., 1997;Vergé et al., 1986;Albert et al., 1990;Palacios et al., 1990;Pompeiano et al., 1992;Khawaja, 1995; Kia et al., 1996a,b;Farde et al., 1997;Raurich et al., 1999;Hume et al., 2001;Maeda et al., 2001;Geyer et al., 2005;Palchaudhuri and Flügge, 2005;Eickhoff et al., 2007;Topic et al., 2007). 5-HT 1A receptors play a role in executive functions, anxiety related behavior, learning and reinforcement, feeding behavior, and locomotor activity (Zilles et al., 2...

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Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Serotonin 5-HT1A receptor binding sites in the brain of the pigeon (Columba livia)

et al. 2012

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“…Several pharmacological studies indicate that endogenous serotonin acts on different receptor subtypes (e.g., 5HT 1 , 5HT 2 , 5HT 3 ), particularly in the forebrain, to inhibit sodium appetite (19,29,52,58,114). Drinking studies in the pigeon suggest that an homologous serotonergic system inhibits fluid intake in both birds and mammals (18). Consistent with the inhibitory effect that serotonin receptor activation has on sodium appetite, early studies also showed that when given systemically, agonists that reduce serotonin release or antagonists that act on 5HT 2 receptors increase sodium intake (29,114).…”

Section: Major Neurohumoral Factors Inhibiting Water And/or Sodium Inmentioning

confidence: 99%

Role of the lateral parabrachial nucleus in the control of sodium appetite

Menani

Luca

Johnson

2014

American Journal of Physiology-Regulatory, Integrative and Comp

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.-In states of sodium deficiency many animals seek and consume salty solutions to restore body fluid homeostasis. These behaviors reflect the presence of sodium appetite that is a manifestation of a pattern of central nervous system (CNS) activity with facilitatory and inhibitory components that are affected by several neurohumoral factors. The primary focus of this review is on one structure in this central system, the lateral parabrachial nucleus (LPBN). However, before turning to a more detailed discussion of the LPBN, a brief overview of body fluid balance-related body-to-brain signaling and the identification of the primary CNS structures and humoral factors involved in the control of sodium appetite is necessary. Angiotensin II, mineralocorticoids, and extracellular osmotic changes act on forebrain areas to facilitate sodium appetite and thirst. In the hindbrain, the LPBN functions as a key integrative node with an ascending output that exerts inhibitory influences on forebrain regions. A nonspecific or general deactivation of LPBN-associated inhibition by GABA or opioid agonists produces NaCl intake in euhydrated rats without any other treatment. Selective LPBN manipulation of other neurotransmitter systems [e.g., serotonin, cholecystokinin (CCK), corticotrophin-releasing factor (CRF), glutamate, ATP, or norepinephrine] greatly enhances NaCl intake when accompanied by additional treatments that induce either thirst or sodium appetite. The LPBN interacts with key forebrain areas that include the subfornical organ and central amygdala to determine sodium intake. To summarize, a model of LPBN inhibitory actions on forebrain facilitatory components for the control of sodium appetite is presented in this review. sodium intake; angiotensin; electrolyte balance; thirst ANIMALS CONSTANTLY LOSE WATER and electrolytes to the external environment, but specific autonomic, hormonal, and behavioral mechanisms operate continuously to adjust and restore body fluid-electrolyte balance. The rate of loss from the kidneys is primarily controlled by neural and hormonal actions, but loss may also occur passively through the largely uncontrolled processes of respiration (evaporation), perspiration, transpiration, and salivation. These later modes of loss are referred to as insensible loss because they cannot be easily measured. Severe loss of both sodium and water may also occur in disorders associated with emesis and diarrhea. However, despite such ongoing challenges, the osmolarity and volume of body fluids are maintained within reasonably narrow limits, thus allowing normal metabolic and cardiovascular functions. Although renal mechanisms can slow water and sodium loss, the restoration of fluid homeostasis is only made possible by the mobilization of behaviors that result in the ingestion of water and sodium (usually NaCl). The behavioral responses of seeking out and consuming water and salty substances involve the motivational states of thirst and salt appetite. Salt appetite is also frequently referred to as sodium appetit...

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“…Each region was measured throughout its rostral-caudal extent. We used canary, zebra finch, chicken, and pigeon atlases [Karten and Hodos, 1967;Stokes et al, 1974;Kuenzel and Masson, 1988;Nixdorf-Bergweiler and Bischof, 2007] along with papers specific to our regions of interest [Sherry et al, 1989;Timmermans et al, 2000;Laverghetta and Shimizu, 2003;Wild, 2004, 2005;Day et al, 2005;Guirado et al, 2005;Yamamoto et al, 2005;Sadananda et al, 2007;Day et al, 2008;Feenders et al, 2008;Watanabe et al, 2008;Atoji and Wild, 2009;Campanella et al, 2009;da Silva et al, 2009;SaintDizier et al, 2009] to identify region boundaries. Specific boundaries for each region are given below.…”

Section: Histology and Morphometricsmentioning

confidence: 99%

Sexually Dimorphic Neural Phenotypes in Golden-Collared Manakins <i>(Manacus vitellinus)</i>

Day

Fusani

Kim³

et al. 2011

Brain Behav Evol

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Male golden-collared manakins (Manacus vitellinus) perform a high-speed acrobatic courtship display punctuated by loud ‘snaps’ produced by the wings. Females join males on display courts to select individuals for copulation; females follow displaying males but do not perform acrobatics or make wing snaps. Sexually dimorphic courtship displays such as those performed by manakins are the result of intense sexual selection and suggest that differences between sexes exist at neural levels as well. We examined sex differences in the volume of brain areas that might be involved in the male manakin courtship display and in the female assessment of this display. We found that males had a larger hippocampus (HP, spatial learning) and arcopallium (AP, motor and limbic areas) than females when adjusted for the size of the telencephalon (TELE) minus the target area. Females had a larger ventrolateral mesopallium (MVL) both when adjusting for the size of the remaining TELE and by direct comparison. The entopallium (E) was not sexually dimorphic. The E is part of the avian tectofugal pathway and the MVL is linked to this pathway by reciprocal connections. The MVL likely modulates visually guided behavior via descending brainstem pathways. We found no sex differences in the volume of the cerebellum or cerebellar nuclei. We speculate that the HP is important to males for cross-season site fidelity and for local spatial memory, the AP for sexually driven motor patterns that are complex in males, and that the MVL facilitates female visual processing in selecting male display traits. These results are consistent with the idea that sexual selection has acted to select sex-specific behaviors in manakins that have neural correlates in the brain.

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Tonic serotonergic control of ingestive behaviours in the pigeon (Columba livia): The role of the arcopallium

Cited by 16 publications

References 91 publications

Serotonin 5-HT1A receptor binding sites in the brain of the pigeon (Columba livia)

Serotonin 5-HT1A receptor binding sites in the brain of the pigeon (Columba livia)

Role of the lateral parabrachial nucleus in the control of sodium appetite

Sexually Dimorphic Neural Phenotypes in Golden-Collared Manakins <i>(Manacus vitellinus)</i>

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