Tongue size matters: revisiting the Mallampati classification system in patients with obstructive sleep apnea

Abstract

Objective: The Mallampati classification system has been used to predict obstructive sleep apnea (OSA). Upper airway soft tissue structures are prone to fat deposition, and the tongue is the largest of these structures. Given that a higher Mallampati score is associated with a crowded oropharynx, we hypothesized that the Mallampati score is associated with tongue volume and an imbalance between tongue and mandible volumes. Methods: Adult males underwent clinical evaluation, polysomnography, and upper airway CT scans. Tongue and mandible volumes were calculated and compared by Mallampati class. Results: Eighty patients were included (mean age, 46.8 years). On average, the study participants were overweight (BMI, 29.3 ± 4.0 kg/m2) and had moderate OSA (an apnea-hypopnea index of 26.2 ± 26.7 events/h). Mallampati class IV patients were older than Mallampati class II patients (53 ± 9 years vs. 40 ± 12 years; p < 0.01), had a larger neck circumference (43 ± 3 cm vs. 40 ± 3 cm; p < 0.05), had more severe OSA (51 ± 27 events/h vs. 24 ± 23 events/h; p < 0.01), and had a larger tongue volume (152 ± 19 cm3 vs. 135 ± 18 cm3; p < 0.01). Mallampati class IV patients also had a larger tongue volume than did Mallampati class III patients (152 ± 19 cm3 vs. 135 ± 13 cm3; p < 0.05), as well as having a higher tongue to mandible volume ratio (2.5 ± 0.5 cm3 vs. 2.1 ± 0.4 cm3; p < 0.05). The Mallampati score was associated with the apnea-hypopnea index (r = 0.431, p < 0.001), BMI (r = 0.405, p < 0.001), neck and waist circumference (r = 0.393, p < 0.001), tongue volume (r = 0.283, p < 0.001), and tongue/mandible volume (r = 0.280, p = 0.012). Conclusions: The Mallampati score appears to be influenced by obesity, tongue enlargement, and upper airway crowding.

Predicción de la vía aérea difícil mediante las escalas Mallampati y Cormack-Lehane durante anestesia general en cirugías de emergencia.

“…En el contexto quirúrgico, la predicción de vía aérea difícil mediante el uso de escalas es indispensable para evitar las complicaciones asociadas en cirugía de emergencia durante la intubación; las lesiones asociadas a vía aérea de difícil intubación son la lesión de tejidos blandos, broncoaspiración, isquemia cerebral o miocárdica (1). Según "American Society of Anesthesiologists" (ASA), las dificultades durante la intubación, se deben principalmente a: intubación esofágica, intubación endotraqueal difícil y ventilación deficiente (2). Una principal causa de morbimortalidad es la intubación endotraqueal difícil, representando el 27% de las complicaciones, previo al acto quirúrgico, en Estados Unidos de Norteamérica (3).…”