Tomographic and histomorphometric evaluation of socket healing after tooth extraction using leukocyte- and platelet-rich fibrin: A randomized, single-blind, controlled clinical trial

Canellas, João Vitor dos Santos; Costa, Rafael Cabral da; Breves, Ricardo Caldeira; Oliveira, Gustavo P.; Figueredo, Carlos Marcelo da Silva; Fischer, Ricardo Guimarães; Thole, Alessandra Alves; Medeiros, Paulo José; Ritto, Fabio

doi:10.1016/j.jcms.2019.11.006

Cited by 60 publications

(98 citation statements)

References 32 publications

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“…Differences in horizontal bone changes between baseline and final follow-up assessed in CBCT scan images were reported in eleven studies (Avila-Ortiz et al, 2020 ;Canellas et al, 2020 ;Cha et al, 2019 ;Clementini et al, 2019 ;Fiorellini et al, 2005 ;Jiang et al, 2017 ;Jung et al, 2013 ;Lim et al, 2019 ;Pang et al, 2016 ;Qabbani et al, 2017 ;Sun et al, 2019 ). Seven studies assessed horizontal changes at different levels (i.e.…”

Section: Radiographic Horizontal Bone Changesmentioning

confidence: 99%

“…Differences in bone volumetric changes between baseline and final follow-up assessed by CBCT scan images were reported in two studies including non-molar teeth (Avila-Ortiz et al, 2020 ;Canellas et al, 2020…”

Section: Volumetric Bone Changes Assessed In Dicom Filesmentioning

confidence: 99%

“…Only five of the included RCTs met all criteria of the Cochrane Collaboration ' s tool for assessing risk of bias (Avila-Ortiz et al, 2020 ;Barone et al, 2017 ;Canellas et al, 2020 ;Clementini et al, 2019 ;Sisti et al, 2012 ). Sixteen studies were categorized as presenting low risk, fourteen of which were RCTs (Araujo et al, 2015 ;Avila-Ortiz et al, 2020 ;Barone et al, 2008Barone et al, , 2017Canellas et al, 2020 ;Cha et al, 2019 ;Clementini et al, 2019 ;Iasella et al, 2003 ;Jung et al, 2013 ;Lim et al, 2019 ;Machtei et al, 2019 ;Rasperini et al, 2010 ;Sisti et al, 2012 ;Sun et al, 2019 ) and two were non-RCTs (Sbordone et al, 2017 ;Zhao et al, 2018 ). Two RCTs were categorized as presenting some concerns (Hauser et al, 2013 ;Pang et al, 2016 ), nine…”

Section: Quality Of Evidencementioning

confidence: 99%

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Post‐extraction dimensional changes: A systematic review and meta‐analysis

Couso‐Queiruga

Stuhr

Tattan

et al. 2020

J Clinic Periodontology

110

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The main goal of dental therapy is to enhance and maintain the general health and well-being of patients (Chapple & Wilson, 2014). Dental extraction is indicated when teeth cannot be maintained in a status compatible with adequate aesthetics, function and/or health, or for strategic reasons (Kao, 2008 ; Tonetti et al., 2000). Beyond its potential impact in quality of life, tooth extraction causes a local physiologic disruption that results in an initial inflammatory response and, subsequently, a variable degree

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Section: Radiographic Horizontal Bone Changesmentioning

confidence: 99%

Section: Volumetric Bone Changes Assessed In Dicom Filesmentioning

confidence: 99%

Section: Quality Of Evidencementioning

confidence: 99%

See 1 more Smart Citation

Post‐extraction dimensional changes: A systematic review and meta‐analysis

Couso‐Queiruga

Stuhr

Tattan

et al. 2020

J Clinic Periodontology

110

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“…Many studies evaluating the effect of PRF in alveolar post-extraction sockets have been carried out in humans. In most of these studies, the use of PRF was clearly beneficial [ 13 , 20 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ], while in others the utility of PRF seemed to be more controversial, failing to show enhancement of the socket healing process [ 31 , 32 , 33 ]. In recent systematic reviews, definitive conclusions could not be drawn [ 34 , 35 , 36 , 37 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Autologous Platelet-Rich Fibrin in Post-Extraction Alveolar Sockets: A Randomized, Controlled Split-Mouth Trial in Dogs with Spontaneous Periodontal Disease

Tambella

Bartocetti

Rossi

et al. 2020

Animals

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Periodontal disease (PD) is a common inflammatory condition in dogs; in severe stages, dental extraction is frequently required. Platelet-rich fibrin (PRF) has been used in human oral surgical procedures and has been experimentally tested on post-extraction sockets in healthy dogs. This is the first split-mouth, randomized, controlled trial designed to compare post-extractive alveolar socket healing with and without topical application of PRF in canine spontaneous PD. Clinical evaluation, radiographic density, and histological scores for inflammation and regeneration were assessed at recruitment (T0) and after a three-week follow up (T1) on 12 dogs, for a total of 31 pairs of sockets. No complications or clinically evident differences between the treated sites and the control sites were observed. Comparing the radiographic densities of the extraction sites measured at T0 and T1, a significant enhancement was observed within the PRF group, but not within control group. The histological score decreased significantly from T0 to T1 within group PRF, but not within the control group; at T1, the PRF group showed a significantly lower histological score than the control group. These findings suggest that PRF could be able to stimulate the natural process of tissue healing and regeneration of post-extraction sites in dogs with spontaneous periodontal disease (PD).

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“…Signi cantly alterations of alveolar bone dimension would occur in these sites. So as to increase the predictability of implant treatment, bone grafting procedures would be necessary at the corresponding period of tooth extraction, prior to or at the corresponding period of implant placement in this type [36][37][38][39]. As such, the long-term tissue stability would be more predictable.…”

Section: Discussionmentioning

confidence: 99%

Classification of Sagittal Root Position and Angulation of Premolars for Immediate Implant Placement: A Cone Beam Computed Tomography Study

Zhan

Wang

Cheng

et al. 2020

Preprint

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Background: Sagittal root position (SRP) and thickness of buccal plate were of clinical guiding significance in implant treatment planning. The study was to classify the SRP and angulations of the maxillary and mandibular premolar to each osseous housing, and to measure the thickness of buccal plate by cone beam computed tomography (CBCT) in order to estimate the distributions and provide clinical decision support. Methods: CBCT images was reviewed on 150 patients who fulfilled the inclusion criteria. The sagittal root position and angulations of the maxillary and mandibular premolars to their respective osseous housing were evaluated and classified using CBCT images. The thickness of buccal plate at 1 mm, 3 mm, 5 mm apical to the alveolar crest was also measured. Results: The frequency distribution of SRP types indicated that, 41.67%, 51.83%, 3.67%, and 2.83% of maxillary premolars; 84.33%, 15%, 0%, and 0.67% of mandibular premolars were classified as type B, M, L, and N. The frequency distribution of angulation classifications indicated that, 20.83%, 46%, 32.17%, and 1% of maxillary premolars; 2%, 5.33%, 36.67%, and 56% of mandibular premolars were classified as class 1, 2, 3, and 4. The buccal bone thickness in most locations of premolar sites was less than 1 mm. Conclusions: The classification of clinical relevance of SRP and angulation of the premolar root to osseous housing would help for treatment planning and improving interdisciplinary communication of immediate implant placement (IIP) in the premolar region.

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Tomographic and histomorphometric evaluation of socket healing after tooth extraction using leukocyte- and platelet-rich fibrin: A randomized, single-blind, controlled clinical trial

Cited by 60 publications

References 32 publications

Post‐extraction dimensional changes: A systematic review and meta‐analysis

Post‐extraction dimensional changes: A systematic review and meta‐analysis

Effects of Autologous Platelet-Rich Fibrin in Post-Extraction Alveolar Sockets: A Randomized, Controlled Split-Mouth Trial in Dogs with Spontaneous Periodontal Disease

Classification of Sagittal Root Position and Angulation of Premolars for Immediate Implant Placement: A Cone Beam Computed Tomography Study

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