Toluidine blue O photodynamic inactivation on multidrug‐resistant <i>pseudomonas aeruginosa</i>

Tseng, Sung-Pin; Teng, Lee‐Jene; Chen, C.T.; Lo, Tzu-Yuan; Hung, Wei‐Chun; Chen, H.J.; Hsueh, Po-Ren; Tsai, Jui‐Chang

doi:10.1002/lsm.20765

Cited by 53 publications

(31 citation statements)

References 40 publications

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“…Several studies have shown that multiresistant microorganisms can be just as susceptible to PDT as similar non-multiresistant strains [34]. However, according to Tegos and Hambin [35] and George et al [36], multiresistant strains can be more difficult to eradicate with PDT compared to antibiotic-susceptible strains.…”

Section: Regardlessmentioning

confidence: 98%

In vitro photoinactivation of bovine mastitis related pathogens

Sellera

Sabino

Ribeiro

et al. 2016

Photodiagnosis and Photodynamic Therapy

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Section: Regardlessmentioning

confidence: 98%

In vitro photoinactivation of bovine mastitis related pathogens

Sellera

Sabino

Ribeiro

et al. 2016

Photodiagnosis and Photodynamic Therapy

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“…A substantial number of studies state that the photodynamic approach can also be used to kill microorganisms, and is considered a promising alternative to treating oral biofilms involved in several major oral diseases such as candidiasis [11,12], dental caries [13], and periodontal disease [14]. In recent years, PACT/PDI has been proposed as an alternative treatment for localized bacterial infections [15].…”

Section: Photodynamic Antimicrobial Chemotherapy In Dentistrymentioning

confidence: 99%

“…A PACT/PDI/PDT regimen can be beneficial for the elimination of microorganisms during systematic therapies of biofilm-dependent diseases, and is able to inactivate some of the known antibiotic-resistant microbial pathogens [15]. Therefore, this approach would be beneficial for the treatment of biofilm-dependent oral diseases, considering the high accumulation of bacteria in the oral environment and the easy access to the site of the disease.…”

Section: Photodynamic Antimicrobial Chemotherapy In Dentistrymentioning

confidence: 99%

Photodynamic and Tissue Tolerable Plasma Therapies as Alternatives to Antimicrobials to Control Pathogenic Biofilms

Paschoal

Dantas

Duarte

2015

Curr Oral Health Rep

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The need for novel antimicrobial techniques has become critical for a number of reasons, including the emergence of resistant strains because of excessive prescription and misuse of antibiotics. The mouth is colonized by a large number of microorganisms. When these microorganisms are organized as biofilms they can contribute to chronic diseases in the human population, such as dental caries, candidiasis, and periodontal disease. Hence, alternative antimicrobial approaches have risen to facilitate the treatment of these diseases. As novel therapies, photodynamic antimicrobial chemotherapy and tissue-tolerable plasma are promising methods that offer the possibility of microbial decontamination with decreased odds for the traditional side effects. Thus, the present review aims to offer an overview and future directions of these new approaches to control pathogenic oral biofilms.

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“…55,56 In a model study, it was demonstrated that 60 MDR Pseudomonas aeruginosa isolates could be killed (up to 6-7 log 10 reduction in viable cell counts) using TBO-PDT. 57 This study also demonstrates that antibiotic-resistant P. aeruginosa was just as susceptible to PDI as antibiotic-susceptible strains. Another report demonstrated that PDI with cationic phthalocyanines has a substantial phototoxic effect in MDR strains of Aeromonas hydrophila.…”

Section: Pdi and Multidrug Effluxmentioning

confidence: 57%