Tolerable pain reduces gastric fundal accommodation and gastric motility in healthy subjects: a crossover ultrasonographic study

Hasuo, Hideaki; Kusunoki, Hiroaki; Kanbara, Kenji; Abe, Tetsuya; Yunoki, Naoko; Haruma, Ken; Fukunaga, Mikihiko

doi:10.1186/s13030-017-0089-5

Cited by 11 publications

(5 citation statements)

References 29 publications

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“…Interestingly, although anaesthesia duration had no influence on PAC rate, horses anesthetized for diagnostic imaging purposes had a significantly lower PAC rate (6.5%) than horses undergoing surgery (16.7% PAC) and horses receiving no opioids postoperatively had a higher PAC (14%) rate than horses receiving butorphanol (5.3%), underscoring the importance of postoperative pain management. Pain initiates a spinal reflex arc, increases sympathetic activity and cortisol and endogenous opioid release, thus inhibiting propulsive gastrointestinal motility (66)(67)(68)(69). Effective pain management is thus crucial to ensure patients' welfare and minimize postoperative morbidity and complications.…”

Section: Discussionmentioning

confidence: 99%

The impact of opioid administration on the incidence of postanaesthetic colic in horses

Haralambus,

Juri,

Mokry

et al. 2024

Front. Pain Res.

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Effective management of postoperative pain is essential to ensure patient welfare, reduce morbidity and optimize recovery. Opioids are effective in managing moderate to severe pain in horses but concerns over their adverse effects on gastrointestinal (GI) motility and associated increased colic risk limit their widespread use. Studies investigating the impact of systemic opioids on both GI motility and colic incidence in horses have yielded inconclusive outcomes. Therefore, this retrospective study aims to assess the influence of systemic administration of butorphanol, morphine, and methadone on post-anaesthetic colic (PAC) incidence. Horses undergoing general anaesthesia for non-gastrointestinal procedures that were hospitalized for at least 72 h post-anaesthesia were included in this study. Anaesthetised horses were stratified by procedure type into horses undergoing diagnostic imaging without surgical intervention, emergency or elective surgery. In addition, patients were grouped by opioid treatment regime into horses receiving no opioids, intraanaesthetic, short- (<24 h) or long-term (>24 h) postoperative opioids. Administered opioids encompassed butorphanol, morphine and methadone. The number of horses showing signs of colic in the 72 h after anaesthesia was assessed for each group. A total of 782 horses were included, comprising 659 undergoing surgical procedures and 123 undergoing diagnostic imaging. The overall PAC incidence was 15.1%. Notably, horses undergoing diagnostic imaging without surgery had a significantly lower PAC rate of 6.5% compared to those undergoing surgery (16.7%, p = 0.0146). Emergency surgeries had a significantly lower PAC rate of 5.8% compared to elective procedures (18%, p = 0.0113). Of the 782 horses, 740 received intraoperative opioids and 204 postoperative opioids, 102 of which long-term (≥24 h). Neither intraoperative (p = 0.4243) nor short-term postoperative opioids (p = 0.5744) increased PAC rates. Notably, only the long-term (≥24 h) administration of morphine significantly increased PAC incidence to 34% (p = 0.0038). In contrast, long-term butorphanol (5.3% PAC, p = 0.8482) and methadone (18.4% PAC, p = 0.6161) did not affect PAC rates. In summary, extended morphine administration was the only opioid treatment associated with a significantly increased risk of PAC.

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Section: Discussionmentioning

confidence: 99%

The impact of opioid administration on the incidence of postanaesthetic colic in horses

Haralambus,

Juri,

Mokry

et al. 2024

Front. Pain Res.

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“…Self-report questionnaire to evaluate alexisomia Each participant was evaluated for potential alexisomic symptoms using the Shitsu-Taikan-Sho Scale (STSS total), a self-report questionnaire consisting of 23 items rated on a scale of 1 to 5, which provides a total score ranging between 23 and 115 (2,6). The STSS total includes the scores on three subcategories: difficulty identifying bodily feelings (DIB), OA, and LHM based on bodily feelings.…”

Section: Methodsmentioning

confidence: 99%

“…TrP diagnosis requires careful manual examination and reliability estimates were generally higher for subjective signs such as tenderness (19). Based on a previous study, palpation was performed when each participant was in a relaxed prone position lying on a bed (6,20). The palpation area was approximately 3 cm wide (horizontal) and 2 cm high (vertical).…”

Section: Ltrp Palpation Proceduresmentioning

confidence: 99%

“…Reduced awareness of bodily feelings that accompany physical diseases is a characteristic of alexisomia, and may affect physical functions (1,2). One study reported reduced gastric motility in healthy volunteers who experienced pain, even though the pain was tolerable (6). A latent trigger point (LTrP) is a tender spot caused by muscle dysfunction found on palpation and does not cause bodily feelings of spontaneous pain (7).…”

Section: Introductionmentioning

confidence: 99%

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Clinical characteristics of alexisomia in patients with incurable cancer

Hasuo

Sakai

2021

Ann Palliat Med

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Background: Alexisomia is a clinical concept that describes difficulties in the awareness and expression of bodily feelings regarding physical diseases and symptoms. The study aim was to investigate whether incurable cancer patients with alexisomia had a higher incidence of latent trigger points, higher pain intensity, and higher pain-improvement goals.Methods: A multicenter cross-sectional survey was conducted among patients with incurable cancer referred to a palliative care service at two university hospitals in Japan. Alexisomia was evaluated using the Shitsu-Taikan-Sho Scale (STSS). All patients were manually examined on their upper trapezius to identify latent trigger points. Patients who experienced pain reported their pain numerical rating scale (PNRS) and personalized pain goal (PPG) scores.Results: A total of 262 patients were selected as participants. Incurable cancer patients with alexisomia were observed in 30.2% of all participants [95% confidence interval (CI): 24.7-35.7]. The latent trigger points risk ratio in the alexisomic group versus the non-alexisomic group was 4.06 (95% CI: 2.24-7.37).Incurable cancer patients with alexisomia tended to have higher PNRS and PPG scores (P<0.001), but there was no significant difference in PPG achievement (P=0.641). Conclusions:In examining incurable cancer patients with alexisomia, we must recognize that their latent trigger points risk ratio and PPGs are higher (lower symptom improvement goals) than cancer patients without alexisomia, and their rate of seeking help for pain may be low.

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“…Research evidence has shown that untreated pain in the early stages of life can lead to devastating effects, which may be short or long term. These effects may be physiological, developmental, emotional, or behavioural and may persist into the later stages of life (Deere et al, 2012;Friedrichsdorf et al, 2015;Hasuo et al, 2017;King et al, 2011;Mathews, 2011). Untreated pediatric pain has been linked with functional disability, longer duration of hospitalization, poor life quality (Friedrichsdorf et al, 2015), and development of chronic pain (Sessle, 2011), which becomes burdensome to affected children, their families, and societies (Bushnell, Čeko, & Low, 2013;Dueñas, Ojeda, Salazar, Mico, & Failde, 2016).…”

Section: Introductionmentioning

confidence: 99%

Children’s Nurses’ Knowledge and Attitudes on Paediatric Pain: A Descriptive Cross-Sectional Survey in a Developing Country

Oduro

Diji

Kusi

et al. 2020

Nurs. Med. J. Nursing

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Background: Children’s nurses’ knowledge of pain affects their pain management practices. Even though poor knowledge and attitudes have been reported in several studies, most were carried out in developed settings. However, little has been reported on the management of paediatric pain by nurses in resource-limited settings such as in sub-Saharan Africa.Purpose: This study sought to assess the knowledge and perceptions of children’s nurses regarding paediatric pain in a Ghanaian context.Methodology: A descriptive cross-sectional survey was carried out among 65 nurses at eight hospitals at various levels of healthcare in Ghana. Over three months, participants’ demographic data and responses on the Pediatric Nurses Knowledge and Attitude Survey Regarding Pain (PNKAS) instrument were collected. Data were analyzed and presented using descriptive and inferential statistics.Results: Participants’ average (SD) knowledge and attitudes regarding paeditric pain was 36.7% (6.9%) and ranged from 21.4% to 57.1%. Pediatric pain knowledge and attitudes (PPKA) of the nurses differed based on working years in the children’s unit and the hospital type they worked in (p<0.05). Nevertheless, the type of hospital facility was the only independent predictor of their PPKA (R2=0.181, p<0.001).Conclusion: Children nurses in this setting generally had insufficient knowledge and attitudes on paediatric pain. They should be motivated to undertake self-directed learning and regular continuing professional education to update their knowledge, attitude and skills on evidence-based pediatric pain assessment and management.

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Tolerable pain reduces gastric fundal accommodation and gastric motility in healthy subjects: a crossover ultrasonographic study

Cited by 11 publications

References 29 publications

The impact of opioid administration on the incidence of postanaesthetic colic in horses

The impact of opioid administration on the incidence of postanaesthetic colic in horses

Clinical characteristics of alexisomia in patients with incurable cancer

Children’s Nurses’ Knowledge and Attitudes on Paediatric Pain: A Descriptive Cross-Sectional Survey in a Developing Country

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