Toksoplazmozisli Koyunlarda Oksidatif Stres ve Seruloplazmin Düzeylerinin Belirlenmesi

Abstract

The aim of the study was to determine the oxidative stress parameters as well as ceruloplasmin levels in sheep with toxoplasmosis. In order to investigate biochemical parameters, a total of 30 sheep were used in the study. According to ELISA test results, 20 sheep were infected with toxoplasmosis, while 10 healthy sheep sera had antibodies negative. Biochemical analysis included total oxidant capacity (TOC), total antioxidant capacity (TAC), oxidative stress index (OSI), nitric oxide (NO) and ceruloplasmin levels. TAC value was found to be statistically significantly lower, and TOC and OSI values were found to be higher in sheep with toxoplasmosis compared to those of the control group. NO and ceruloplasmin values were nonsignificantly. As a result, it was concluded from the data in the study that toxoplasmosis caused changes in oxidant and antioxidant capacity in sheep.

Investigation of Aopp, Total Sulphydryl Group (T-sh), Seroplasmin Levels in Sheep Wi̇th Zoonotic Liver Parasitosis

“…Ceruloplasmin has functions such as increasing various enzyme (cytochrome C oxidase and Cu-Zn superoxide dismutase) activities with copper, providing higher antimicrobial power in phagocytic cells and protecting against oxidative damage (Bayyit and Merhan, 2020). moreover, ceruloplasmin is an indicator of the presence of infection (Bozukluhan et al, 2016;Bayyit and Merhan, 2020).…”

“…Ceruloplasmin, which is involved in the antioxidant system, is a moderately important acute phase protein in addition to its functions such as protecting cells against oxidative damage and antimicrobial activity (Bozukluhan et al, 2020). Bozukluhan et al, (2020) reported that the value of ceruloplasmin was found to be high in sheep with toxoplasmosis, but this was statistically insigni cant.…”

“…Ceruloplasmin, which is involved in the antioxidant system, is a moderately important acute phase protein in addition to its functions such as protecting cells against oxidative damage and antimicrobial activity (Bozukluhan et al, 2020). Bozukluhan et al, (2020) reported that the value of ceruloplasmin was found to be high in sheep with toxoplasmosis, but this was statistically insigni cant. Similarly, in another study, Nispet et al, (2008) compared the serum ceruloplasmin level in cattle with echinococcosis with the healthy group and reported that the difference in ceruloplasmin values was insigni cant.…”

“…Phagocytic cells play an important role in live defense. While performing these functions, they generate free radicals (such as hydrogen peroxide, super oxide anion) due to excessive oxygen consumption (Bozukluhan et al, 2016;Çenesiz 2020). Oxidative stress caused…”

Buzağılarda Göbek Bölgesi Lezyonlarının Klinik ve Sağaltım Yönünden Değerlendirilmesi: 100 Olgulu Retrospektif Bir Çalışma

“…Araştırmacılar (3,5,20) göbek kordonundaki enfeksiyon etkenlerinin portal ven aracılığı ile eklem gibi daha uzak yapılara yayılarak artrit başta olmak üzere çeşitli sekonder hastalıklar oluşturduğunu ve omfaloflebitis vakalarının %50 sinden fazlasında en sık gözlenen komplikasyonun septik artritis olduğunu bildirmişlerdir (5,18). Sunulan bu çalışmada topallık problemi ile getirilen buzağıların klinik muayeneleri neticesinde göbek bölgesi lezyonu gösteren (omfalitis, omfaloflebitis, omfaloarteritis) 64 olguda 29 adet (%45.31) monoartrit ve 12 adet (%18.75) poliartrit olmak üzere toplam 41 artritli (% 64.06) buzağı tespit edildi.…”