1995
DOI: 10.1055/s-2007-994478
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Tocolysis in Advanced Preterm Labor: Impact on Neonatal Outcome

Abstract: Chart review of 73 patients with 3.5 cm or more dilation, intact membranes, and regular contractions at less than 36 weeks. Forty-four (group A) received tocolysis with magnesium sulfate, and 13 of the 44 also received indomethacin. Twenty-nine (group B) received no tocolysis. Obstetric and neonatal outcomes were compared. Demographic factors and admission gestational age, cervical dilation, effacement, and uterine activity were similar. Twenty-one of the 44 in group A versus 3 of 29 in group B had delivery de… Show more

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Cited by 22 publications
(5 citation statements)
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“…These patients may require combined use of tocolytic agents like intravenous magnesium sulfate and oral indomethacin to achieve longer duration of successful tocolysis. 16,17 In summary, our study shows that women with preterm uterine contractions presenting at 1-cm dilatation are at significant risk for preterm delivery: 19/94 (20%) at < 32 weeks and 40/104 (38%) at < 35 weeks. Because the diagnosis of early preterm labor remains difficult, we recommend that patients presenting to labor and delivery with regular uterine contractions especially at < 32 weeks' gestation should be observed for at least 24 hours prior to discharge.…”
Section: Discussionmentioning
confidence: 68%
“…These patients may require combined use of tocolytic agents like intravenous magnesium sulfate and oral indomethacin to achieve longer duration of successful tocolysis. 16,17 In summary, our study shows that women with preterm uterine contractions presenting at 1-cm dilatation are at significant risk for preterm delivery: 19/94 (20%) at < 32 weeks and 40/104 (38%) at < 35 weeks. Because the diagnosis of early preterm labor remains difficult, we recommend that patients presenting to labor and delivery with regular uterine contractions especially at < 32 weeks' gestation should be observed for at least 24 hours prior to discharge.…”
Section: Discussionmentioning
confidence: 68%
“…Similar results were found in different control trials. This study shows that nifedipine is a better choice for tocolysis 16 , compared with salbutamol in view of less maternal side effects and comparable results regarding prolongation of pregnancy and neonatal outcome.…”
Section: Uterine Contractionsmentioning
confidence: 63%
“…However, data on tocolysis and advanced preterm labor are limited and the appropriate management is controversial. [ 12 13 14 ]…”
Section: Discussionmentioning
confidence: 99%