Tobacco smoking and binge alcohol use are associated with incident venous thromboembolism in an HIV cohort

Luu, Brandon; Ruderman, Stephanie A; Nance, Robin M.; Delaney, Joseph A.; Ma, Jimmy; Hahn, Abigail; Heckbert, Susan R.; Budoff, Matthew J.; Crothers, Kristina; Mathews, William C; Christopolous, Katerina; Hunt, Peter W.; Eron, Joseph J.; Moore, Richard D.; Keruly, Jeanne C.; Lober, William B.; Burkholder, Greer A.; Willig, Amanda L.; Chander, Geetanjali; McCaul, Mary E.; Cropsey, Karen L.; O’Cleirigh, Conall; Peter, Inga; Feinstein, Matthew J.; Tsui, Judith I.; Lindströem, Sara; Saag, Michael S.; Kitahata, Mari M.; Crane, Heidi M.; Drumright, Lydia N; Whitney, Bridget M

doi:10.1111/hiv.13309

Cited by 1 publication

(2 citation statements)

References 88 publications

(124 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We created a continuous variable from the categorical response options to measure VN use per 30 days, as we have done in previous studies. 43 The transformation used 0 for a response of “Never in the past 12 months,” 0.5 for “Once or a few times in the past 12 months,” 1 for “Once or a few times a month,” 4 for “Once or a few times a week,” and 30 for “Every day or almost every day.” CC smoking was measured as never, former, or current use. The Alcohol Use Disorders Identification Test Consumption (AUDIT-C) scale in combination with clinical and self-reported information was used to measure alcohol consumption as no current use, no current use with a prior alcohol use disorder (AUD), current nonhazardous use, and current hazardous use.…”

Section: Methodsmentioning

confidence: 99%

Section: Substance Usementioning

confidence: 99%

See 1 more Smart Citation

Vaporized Nicotine (E-Cigarette) and Tobacco Smoking Among People With HIV: Use Patterns and Associations With Depression and Panic Symptoms

Hahn

Ruderman

Nance

et al. 2023

JAIDS Journal of Acquired Immune Deficiency Syndromes

Self Cite

View full text Add to dashboard Cite

Background:Vaporized nicotine (VN) use is increasing among people with HIV (PWH). We examined demographics, patterns of use, depression, and panic symptoms associated with VN and combustible cigarette (CC) use among PWH.Methods:We analyzed VN use among PWH in care at 7 US sites. PWH completed a set of patient-reported outcomes, including substance use and mental health. We categorized VN use as never vs. ever with the frequency of use (days/month) and CC use as never, former, or current. We used relative risk regression to associate VN and CC use, depression, and panic symptoms. Linear regression estimated each relationship with VN frequency. Models were adjusted for demographics.Results:Among 7431 PWH, 812 (11%) reported ever-using VN, and 264 (4%) reported daily use. Half (51%) of VN users concurrently used CC. VN users were more likely than those without use to be younger, to be White, and to report ever-using CC. PWH reporting former CC use reported ≥8.5 more days per month of VN use compared with never CC use [95% confidence interval (95% CI): 5.5 to 11.5 days/month] or current CC use (95% CI: 6.6 to 10.5 days/month). Depression (relative risk: 1.20 [95% CI: 1.02 to 1.42]) and panic disorder (1.71 [95% CI: 1.43 to 2.05]) were more common among PWH ever-using VN. Depression was common among PWH using VN (27%) and CC (22%), as was panic disorder (21% for VN and 16% for CC).Conclusion:Our study elucidated demographic associations with VN use among PWH, revealed the overlap of VN and CC use, and associations with depression/panic symptoms, suggesting roles of VN in self-medication and CC substitution, warranting further longitudinal/qualitative research.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Substance Usementioning

confidence: 99%

Vaporized Nicotine (E-Cigarette) and Tobacco Smoking Among People With HIV: Use Patterns and Associations With Depression and Panic Symptoms

Hahn

Ruderman

Nance

et al. 2023

JAIDS Journal of Acquired Immune Deficiency Syndromes

Self Cite

View full text Add to dashboard Cite

show abstract

Tobacco smoking and binge alcohol use are associated with incident venous thromboembolism in an HIV cohort

Abstract: Among 13,506 people with HIV (PWH) over 4 years median follow-up, we observed a 1.6-fold increased risk of type-1 (T2MI) and type-2 (T2MI) myocardial infarction for current versus never smoking. Women had higher risk of T2MI than men and vice-versa.

Cited by 1 publication

References 88 publications

Vaporized Nicotine (E-Cigarette) and Tobacco Smoking Among People With HIV: Use Patterns and Associations With Depression and Panic Symptoms

Vaporized Nicotine (E-Cigarette) and Tobacco Smoking Among People With HIV: Use Patterns and Associations With Depression and Panic Symptoms

Contact Info

Product

Resources

About