Tobacco and alcohol as factors for male infertility—a public health approach

Abstract

Background The study of reproductive characteristics of 430 male subjects of different age, fertility status and educational level who were involved in the program of extracorporeal fertilization at the Clinic of Gynecology and Obstetrics, Clinical Centre Niš, examined their knowledge, attitudes and behavior regarding tobacco and alcohol consumption as lifestyle risk predictors of their partial or full infertility. Methodology Consisted of the analyses of spermiograms to establish their fertility status and a survey of their attitudes towards smoking and alcohol use (behavior, knowledge of the general health and reproductive health consequences of such a lifestyle, and their determination to change it). Results The proportion with higher tobacco consumption and more severe forms of infertility increased significantly with ageing (P < 0.001); the highest daily consumption of alcohol and the incidence of intoxication was seen among azoospermic patients; the level of awareness of the harmful effects of tobacco was highest among normozoospermic subjects and the highest level of determination to quit smoking was statistically significantly present among azoospermic subjects. Conclusion Appropriate use of health promotion activities in relation to alcohol and tobacco use is through specially designed programs.

A bidirectional causal relationship study between mental disorders and male and female infertility

“…Not only did our study demonstrate that infertility can slightly increase the risk of women developing bipolar disorder, but the MVMR analysis also found that alcoholic drinks per week appeared to reduce this risk. However, given the negative effects of alcohol on fertility, this form of relief for psychiatric disorders needs to be used with caution ( 58 , 59 ).…”

Genetically predicted asthma and the risk of abnormal spermatozoa

“…To date, the cause of male infertility has not been fully elucidated yet. Still, most of the time, it can be related to overweight, diabetes ( Service et al, 2023 ), and poor lifestyle habits such as smoking ( Sharma et al, 2016 ) and alcohol consumption ( Basic et al, 2023 ), which may impair spermatogenesis and eventually lead to the production of abnormal spermatozoa. Moreover, It was reported that more than 2% of infertile men exhibit abnormal spermatozoa ( Kumar and Singh, 2015 ).…”

Advances in Epigenetic Mechanisms and Transgenerational Inheritance of Male Infertility Induced by Exposure to Endocrine-Disrupting Chemicals

“…Many factors can cause male infertility, mainly known as Klinefelter syndrome, varicocele, environmental or occupational exposure to toxic chemicals [4], heavy metals [5,6], smoking [7] and drinking [8], etc. Experimental and epidemiological studies show a strong connection between exposure to environmental endocrinedisrupting chemicals (EDCs) and impaired male fertility [9][10][11].…”