To Study the Utilization Pattern of Nasal Decongestants and their Effects on Heart Rate and Blood Pressure

Chopra, Abhishek

doi:10.5005/jp-journals-10013-1126

An International Journal Clinical Rhinology

2012

DOI: 10.5005/jp-journals-10013-1126

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To Study the Utilization Pattern of Nasal Decongestants and their Effects on Heart Rate and Blood Pressure

Abhishek Chopra¹

Abstract: Background: Nasal decongestants (NDs) are frequently prescribed over the counter (OTC) drugs for cough and cold. These are sympathomimetic drugs, which act through  1 and  1 adrenoceptors to cause vasoconstriction and positive inotropic, chronotropic and dromotropic effect on the heart. This study was conducted to assess the pattern of utilization of the NDs and their effect on heart rate (HR) and blood pressure (BP). Patients were observed for any other adverse drug reactions (ADRs). Materials and methods:R… Show more

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Cited by 2 publications

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Evaluation of Symptomatic Treatment Approaches of Pediatricians for Pediatric Patients with Upper Respiratory Tract Infection Regarding to Rational Drug Use

İzgi¹,

Yilmaz²,

Oğuz³

et al. 2022

jcp

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Introduction: Prescribing a large number of drugs for symptomatic treatment of upper respiratory tract infection (URTI) can cause more frequent drug interactions and an increase in undesirable side effects in pediatric patients. The aim of this retrospective study is to evaluate the drug prescriptions for symptomatic treatment to pediatric patients diagnosed with URTI in terms of rational drug use. Materials and Methods: Fourteen pediatric outpatient clinics of ŞanlıurfaTraining and Research Hospital were included in the study. The number of samples was determined as 1064. The first 76 prescriptions of the pediatricians written for patients diagnosed as URTI were selected retrospectively by using the Hospital Information Management System. Results: There was an average of 4 and a maximum of 9 drugs, whereas the number of active substances was between 6 and 19 in prescriptions. Analgesics-antipyretics (86.7%) and antibiotics (69.1%) were most prescribed, followed by decongestants (47.9%) and antihistamines (47.1%). Analgesic-antipyretics (36.4%) was the most preferred drug group among the drugs used in symptomatic treatment whereas antiseptics was the least (0,9%). Active ingredients prescribed more than once due to combined preparations were analgesics (36.2%), expectorants (18.7%), decongestants (16.5%), antihistamines (8.8%) vitamins (5%) respectively. Antihistamines (21.8%), decongestants (21.2%), and cough suppressants (16.8%) were used at inappropriately high doses. Decongestants were used mostly in inappropriate dosing interval, compared to other groups (20.8%). When assessed according to physician prescriptions, drugs used in symptomatic treatment, drug combinations from the same group, preference for local or systemic use, and inappropriate doses of antihistamines and decongestants were statistically different among physicians. Conclusion:This study shows that some of the specialist physicians currently prescribe incompatible with the principles of rational drug use in the symptomatic treatment of children with a diagnosis of URTI. Continuous in-service training could increase the awareness of physicians on this subject and keep their knowledge up-to-date. Additionally, establishing a warning system or making limitations during e-prescription may also be useful.

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Evaluation of Symptomatic Treatment Approaches of Pediatricians for Pediatric Patients with Upper Respiratory Tract Infection Regarding to Rational Drug Use

İzgi¹,

Yilmaz²,

Oğuz³

et al. 2022

jcp

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show abstract

Assessment of the Prevalence of the Use of Nasal Decongestants Among the General Population in Saudi Arabia

Alharthi¹,

Altowairqi²,

Alswat³

et al. 2022

Cureus

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BackgroundA topical nasal decongestant (NDC) is widely prescribed in ENT practice and used as self-medication because it is available over the counter, which makes it an easily accessible medication. Due to its common and long-term use, it is associated with serious nasal complications. It is commonly self-administrated in many otolaryngology diseases like the common cold, sinusitis, and acute or chronic rhinitis. The long-term usage of nasal decongestants is associated with significantly increased side effects. AimTo assess the prevalence of the usage of nasal decongestants among the general population in Saudi Arabia ad the pattern of its use. MethodologyA questionnaire-based, cross-sectional survey was applied to level all available populations in Saudi Arabia. Participants with ages aged 10 to 60 years old in Saudi Arabia were invited to participate in the survey. Data were collected from participants using a predesigned online questionnaire. The questionnaire included the participant's demographic data, NDC use, and pattern of use. The questionnaire was uploaded online by researchers and their friends using social media platforms. ResultsA total of 1456 participants completed the study questionnaire. Participants ages ranged from 10 to 60 years with a mean age of 26.9 ± 12.4 years old. Exact 585 (40.2%) participants were males and 1270 (87.2%) were from urban regions. A total of 657 (45.1%) respondents reported using nasal decongestants while 799 (54.9%) did not use NDC. As for the duration of use, 70.8% used NDC for less than five days and 13.5% used it for 5-15 days. The most reported causes of using NDC were nasal obstruction (62.7%) and common cold (25.7%). ConclusionsIn conclusion, the study revealed that the frequency of using nasal decongestants was common (45.1%) in the study. More efforts should be paid to improve public awareness regarding indications, duration of use, and method of using nasal decongestants to avoid rebound reactions that may affect patients' daily life activities.

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To Study the Utilization Pattern of Nasal Decongestants and their Effects on Heart Rate and Blood Pressure

Cited by 2 publications

References 12 publications

Evaluation of Symptomatic Treatment Approaches of Pediatricians for Pediatric Patients with Upper Respiratory Tract Infection Regarding to Rational Drug Use

Evaluation of Symptomatic Treatment Approaches of Pediatricians for Pediatric Patients with Upper Respiratory Tract Infection Regarding to Rational Drug Use

Assessment of the Prevalence of the Use of Nasal Decongestants Among the General Population in Saudi Arabia

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