To study Anti-inflammatory activity of 70% Methanolic Extract of<i>Triumfetta rhomboidea</i>: In Vitro Study

Thawkar, Baban S; Kale, Mrudula; Oswal, M.; Maniyar, K.; Kadam, K Rupali; Kamat, S. D.

doi:10.5958/0974-360x.2016.00044.5

Cited by 7 publications

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“…Various studies indicated that T. rhomboidea posseses anti-inflammatory, anticancer, antioxidant, hepatoprotective, antibacterial, antimicrobial, anti-diabetic, antitubercular and anthelmintic, chemopreventive and lactogenic activity. 14 The isolation of flavone glycosidal derivative of Scutellarein, Triumboidin, from the leaves of T. rhomboidea was reported by Shrinivasan and Subramanian who wrongly characterized it as Scutellarein-7-O-L-rhamnosylarabinoside and also no evidence was provided for the presence of the disaccharide moiety. 15 Again further investigation was done on the same compound, Triumboidin, by Bernard Voirin and Jean Favre-bonvin using conventional extraction methodology i.e boiling with 80% of ethanol.…”

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confidence: 99%

Comparative Extraction and Quantification of Scutellarein from Leaves of Triumfetta rhomboidea Using RP-HPLC

Kendre¹,

Wakte²

2023

Ind. J. Pharm. Edu. Res

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Aim: The purpose of this paper was to develop a sensitive, reproducible Reverse Phase High Performance Liquid Chromatography (RP-HPLC) for extraction and quantitative estimation of Scutellarein, major flavone glycoside from leaves of Triumfetta rhomboidea. Materials and Methods: To optimize best solvent system and ideal extraction methodology, various leaves extract was prepared by using different solvent systems such as ethanol, ethanol: water (50:50) and water through different extraction methodologies includes, maceration, Soxhlet assisted extraction (SAE), Ultrasound Assisted Extraction (UAE) and Accelerated Solvent Extraction (ASE). Chromatographic separation of Scutellarein was performed on C 18 column. Results:The results showed that the highest concentration of Scutellarein was found to be 1.547 ng in ethanolic extract. This study states about, existence of flavone glucocidic content in leaves extract of Triumfetta rhomboidea which can be extracted using ethanol as best solvent system and ASE as optimized extraction methodology. Conclusion: Extracts from T. rhomboidea obtained by maceration, SAE, UAE and ASE methods were analysed by HPLC-ESI-MS/MS to quantify flavonoid scutellarein contents. Ethanol was found to be a promising solvent system and Accelerated Solvent Extraction methodology was found to be the promising methodology for the extraction of Scutellarein from leaves of Triumfetta rhomboidea.

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Section: Introductionmentioning

confidence: 99%

Comparative Extraction and Quantification of Scutellarein from Leaves of Triumfetta rhomboidea Using RP-HPLC

Kendre¹,

Wakte²

2023

Ind. J. Pharm. Edu. Res

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Caffeine-loaded gold nanoparticles conjugated with PLA-PEG-PLA copolymer for in vitro cytotoxicity and anti-inflammatory activity

Kamalakannan

Gajendiran

Prabakaran

et al. 2017

Journal of Industrial and Engineering Chemistry

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Use of herbal formulations for the treatment of circumcision wounds in Eastern and Southern Africa

Maroyi¹

2021

Plant Sci. Today

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Medicinal plants used to treat and manage circumcision wounds have remained an integral part of traditional practice in Eastern and Southern Africa. This study reviews the traditional usage of medicinal plants to treat and manage circumcision wounds in Eastern and Southern Africa. Drawing on data from Kenya, Namibia, South Africa and Tanzania, information was collected from different sources including books, theses and electronic scientific search engines such as Scopus, Science Direct, PubMed, SciFinder and Google Scholar. A literature search was also undertaken focusing on medicinal plants used against circumcision wounds that demonstrated antibacterial and anti-inflammatory activities in in vitro studies. Twenty-eight medicinal plants from 15 families are recorded as traditional therapies for circumcision wounds following an extensive literature search. These species used to treat and manage circumcision wounds, and as dressing after circumcision to prevent serious inflammation are mainly (64.3%) members of Amaryllidaceae, Asparagaceae, Asteraceae, Euphorbiaceae and Fabaceae families. Three quarters (75.0%) of these species including Acalypha ornata, Achyranthes aspera, Asparagus africanus, Boophone disticha, Brunsvigia grandiflora, Burkea africana, Colophospermum mopane, Datura stramonium, Dichrostachys cinerea, Helichrysum appendiculatum, H. foetidum, H. longifolium, H. nudifolium, H. pedunculatum, Lippia javanica, Maesa lanceolata, Ptaeroxylon obliquum, Ricinus communis, Searsia natalensis, Triumfetta rhomboidea and Vachellia nilotica have shown antibacterial and anti-inflammatory effects in a set of in vitro models. Further studies are needed such as isolation of phytochemical compounds, in vivo activities, clinical and toxicological studies.

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To study Anti-inflammatory activity of 70% Methanolic Extract ofTriumfetta rhomboidea: In Vitro Study

Cited by 7 publications

References 0 publications

Comparative Extraction and Quantification of Scutellarein from Leaves of Triumfetta rhomboidea Using RP-HPLC

Comparative Extraction and Quantification of Scutellarein from Leaves of Triumfetta rhomboidea Using RP-HPLC

Caffeine-loaded gold nanoparticles conjugated with PLA-PEG-PLA copolymer for in vitro cytotoxicity and anti-inflammatory activity

Use of herbal formulations for the treatment of circumcision wounds in Eastern and Southern Africa

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