To Investigate the Relationship Between the Grade of Blepharitis with Presence of Demodex Spp. in Patents with Chronic Anterior Blepharitis

Altınkurt, Emre; Müftüoğlu, Orkun; Uğurlu, Adem; Tosun, Ayşe İstanbullu; Aydin, Rukiye; Avci, O

doi:10.5336/ophthal.2016-52878

Cited by 5 publications

(1 citation statement)

References 11 publications

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“…15 The higher infestation rate in other studies could be due to the fact that detection of D. brevis has been much less in our study. 8,14,[17][18][19][20][21][22] However, in most of the studies carried out, the Demodex species was not specified or mites were only identified up to the genus level. In this context, detection of the incidence as well as identification of the species of Demodex has been done in our study.…”

Section: Discussionmentioning

confidence: 99%

Occurrence of Demodex infestation in chronic blepharitis in a tertiary care hospital in North-East India

Hazarika

Ghuge

2021

Int J Community Med Public Health

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Background: Chronic blepharitis is frequently encountered by ophthalmologists. Demodex mites (Demodex folliculorum and Demodex brevis) can play a role in its pathogenesis, especially in treatment-resistant cases. Demodex infestation often remains underdiagnosed and undertreated. Definitive diagnosis can be made with lash-sampling. Objective of the study was to find the association between Demodex infestation and chronic blepharitis.Methods: The study included 80 patients diagnosed with chronic blepharitis and 80 controls without blepharitis. Four eyelashes were epilated from each lower and upper lids of the right and left eye (a total of sixteen samples) of each participant. Eyelash samples were examined under a light microscope and Demodex species were identified and counted.Results: Demodex mites were detected in 45 cases (56.25%) and 14 controls (17.5%). Significant association was found between demodex infestation and blepharitis as odd’s ratio was found to be 6.0612 and p value <0.0001. D. folliculorum was detected in 42 cases, D. brevis in 2 cases while in one case, both were detected. The mean age for Demodex positive cases and controls were 49.78±13.25 and 64±7.86 years, respectively. Amongst the cases, Demodex was detected in 57.69% males (30 out of 52) and 53.55% females (15 out of 28).Conclusions: There is significant co-relation between Demodex infestation and chronic blepharitis. Demodex infestation should be part of the differential diagnosis of chronic blepharitis.

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Section: Discussionmentioning

confidence: 99%

Occurrence of Demodex infestation in chronic blepharitis in a tertiary care hospital in North-East India

Hazarika

Ghuge

2021

Int J Community Med Public Health

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Prevalence and identification of demodex spp related to patients with blepharitis among some Iraqi population in Baghdad city

Khalil¹,

Al-Kamil²

2022

1st Samarra International Conference for Pure and Applied Sciences (Sicps2021): Sicps2021

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Prevalence and Load ofDemodex folliculorumandDemodex brevis(Acari: Demodicidae) in Patients With Chronic Blepharitis in the Province of Erzincan, Turkey

Zeytun

Karakurt

2018

Journal of Medical Entomology

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Chronic blepharitis is an ocular disease frequently encountered by ophthalmologists. Demodex mites can play a role in the pathogenesis of blepharitis along with bacterial agents, especially in treatment-resistant cases or recurrent cases after treatment. This study was performed to determine the prevalence and load of Demodex folliculorum (Simon) and Demodex brevis Akbulutova in chronic blepharitis patients and to assess the relationship between the prevalence and load of Demodex species and ocular symptoms. The study included 365 patients diagnosed with chronic blepharitis in clinical examination, and 175 controls without any chronic or ocular disease. In the study, two eyelashes were sampled from the lower and upper lids of the right and left eyes (a total of eight samples) of the participants. Eyelash samples were examined under a light microscope, and Demodex species were identified and counted. Demodex were detected in 79.2% (95% CI: 75-83%) of patients and 31.4% (95% CI: 24-38%) of controls in this study. D. folliculorum alone (mean: 4.96; min: 1; max: 17; P < 0.001) was detected in 72.3% of patients, in 0.7% D. brevis alone (mean: 1.00, P > 0.05), and in 27% both D. folliculorum and D. brevis (mean: 21.65; min: 2; max: 79; P < 0.001). In Demodex positive controls, only D. folliculorum (mean: 2.38; min: 1; max: 6) was detected while there was no D. brevis. Nevertheless, mean ocular symptom scores were significantly higher in Demodex positive patients than in Demodex negative patients (P < 0.001). Itching, foreign body sensation, and redness were the most common complaints in Demodex positive patients. As a result, Demodex mites were high in numbers in patients with chronic blepharitis in Erzincan. There was a positive correlation between Demodex mites and chronic blepharitis and ocular symptoms. It may be helpful to consider these findings in clinical assessment of blepharitis patients.

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To Investigate the Relationship Between the Grade of Blepharitis with Presence of Demodex Spp. in Patents with Chronic Anterior Blepharitis

Cited by 5 publications

References 11 publications

Occurrence of Demodex infestation in chronic blepharitis in a tertiary care hospital in North-East India

Occurrence of Demodex infestation in chronic blepharitis in a tertiary care hospital in North-East India

Prevalence and identification of demodex spp related to patients with blepharitis among some Iraqi population in Baghdad city

Prevalence and Load ofDemodex folliculorumandDemodex brevis(Acari: Demodicidae) in Patients With Chronic Blepharitis in the Province of Erzincan, Turkey

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