To Analyze the Influencing Factors of Senile Coronary Heart Disease Patients Complicated with Frailty Syndrome

Qin, Tian; Wang, Sheng; Guoheng, Hu

doi:10.1155/2022/7619438

Cited by 6 publications

(6 citation statements)

References 19 publications

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“…Its increase meant that body had continuous inflammation. In addition, the increasing levels of IL-6 were associated with some frailty features such as weight loss, bone density reduction, and thrombocytosis [26]. It was thus suggested that proactive methods to control chronic inflammation in elderly male COPD patients could reduce the frailty risk to certain extent.…”

Section: Factorsmentioning

confidence: 99%

Incidence of frailty and construction of prediction model in elderly male patients with chronic obstructive pulmonary disease

2023

Journal of Men's Health

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The incidence of frailty was studied and prediction model was constructed for the elderly male patients with chronic obstructive pulmonary disease (COPD). Total of 266 elderly males having COPD were selected, and Fried Frailty Phenotype was employed to investigate their frailty status. According to the clinical experience, literature and reports; age, BMI (Body Mass Index), course and condition of COPD, laboratory findings, lung function, life quality, nutritional status and disease acceptance were designated as independent variables; and the incidence of frailty was taken as dependent variable. A binary logistic regression model was applied to analyze the factors affecting incidence of frailty, and a prediction model was constructed for the clinical screening of elderly male COPD patients at high frailty risk. The scores of 266 elderly male COPD patients investigated by frailty phenotype (FP) phenotype ranged from 0 to 5, and mean score was 1.83 ± 0.43. Total of 103 patients scored more than 3 among these patients. The frailty detection rate was 38.72%. Multi-factors logistic regression analysis suggested that age, hospitalization for acute exacerbation of COPD within a year, and interleukin 6 (IL-6) levels were the risk factors for incidence of frailty in elderly male COPD patients, while FEV1 (Forced Expiratory Volume in 1 second) and MNA-SF (Mini Nutritional Assessment Short-Form) levels were the protective factors. COPD frailty was higher in elderly men. Age, inflammatory response, lung function, disease control and nutritional status were the independent factors affecting incidence of frailty. Strengthening the screening for frailty in elderly patients and monitoring their inflammatory response, lung function, and nutritional status were significant in reducing incidence and improving prognosis.

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Section: Factorsmentioning

confidence: 99%

Incidence of frailty and construction of prediction model in elderly male patients with chronic obstructive pulmonary disease

2023

Journal of Men's Health

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“…During the 6-year follow-up of the NHATS study, it was revealed that seniors with pre-frailty and frailty have higher incidences of all-cause mortality, mainly due to death, stroke and peripheral vascular disease. The means to include frailty evaluation into the care of seniors at risk for CCSs is limited due to low efficacy in the prevention of frailty, no fully efficient therapies of the frailty and limited access to comprehensive geriatric evaluation [ 46 , 47 , 48 ].…”

Section: Risk Assessment In the Frail Senior Patient With Ccsmentioning

confidence: 99%

Chronic Coronary Syndrome in Frail Old Population

Ilie

Țăranu

Ștefăniu

et al. 2022

Life

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The demographic trend of aging is associated with an increased prevalence of comorbidities among the elderly. Physical, immunological, emotional and cognitive impairment, in the context of the advanced biological age segment, leads to the maintenance and precipitation of cardiovascular diseases. Thus, more and more data are focused on understanding the pathophysiological mechanisms underlying each fragility phenotype and how they potentiate each other. The implications of inflammation, sarcopenia, vitamin D deficiency and albumin, as dimensions inherent in fragility, in the development and setting of chronic coronary syndromes (CCSs) have proven their patent significance but are still open to research. At the same time, the literature speculates on the interdependent relationship between frailty and CCSs, revealing the role of the first one in the development of the second. In this sense, depression, disabilities, polypharmacy and even cognitive disorders in the elderly with ischemic cardiovascular disease mean a gradual and complex progression of frailty. The battery of tests necessary for the evaluation of the elderly with CCSs requires a permanent update, according to the latest guidelines, but also an individualized approach related to the degree of frailty and the conditions imposed by it. By summation, the knowledge of frailty screening methods, through the use of sensitive and individualized tools, is the foundation of secondary prevention and prognosis in the elderly with CCSs. Moreover, a comprehensive geriatric assessment remains the gold standard of the medical approach of these patients. The management of the frail elderly, with CCSs, brings new challenges, also from the perspective of the treatment particularities. Sometimes the risk–benefit balance is difficult to achieve. Therefore, the holistic, individualized and updated approach of these patients remains a desired objective, by understanding and permanently acquiring knowledge on the complexity of the frailty syndrome.

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“…Currently, tuberculosis continues to be one of the most significant infectious diseases threatening global human health. Frailty [1] refers to a syndrome in which the elderly experience a decrease in physiological reserve, thereby increasing their vulnerability. Due to this reduced capacity to withstand stress, even minor external stimuli can result in adverse outcomes such as acute illness, disability, falls, delirium, and mortality.…”

Section: Introductionmentioning

confidence: 99%

Correlation between depression and adherence to respiratory function exercise in elderly frail patients with tuberculosis: A cross-sectional survey

Si,

Guo,

Feng

et al. 2024

Medicine

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Background: We investigated the current state of frailty in elderly patients with tuberculosis and analyzed the factors that influence it. Methods: Using a convenience sampling method, 120 elderly patients with tuberculosis were selected from the Department of Infectious Diseases at Lishui Hospital of Traditional Chinese Medicine in Zhejiang Province. A cross-sectional survey was conducted using general demographic questionnaires, the FRAIL (fatigue, resistance, aerobic capacity, illnesses, and loss of weight) screening scale, the self-rating depression scale (SDS), and a questionnaire on respiratory function exercise adherence. The influencing factors for depression were analyzed using logistic regression. Results: The average depression score of the 120 elderly patients with frailty and tuberculosis was 54.88 ± 5.61, indicating a mild level of depression. The correlation between this score and respiratory function exercise adherence was negative. According to a logistic regression analysis, marital status and payment methods were influencing factors for depression in these elderly patients with frailty and tuberculosis. Conclusion: There is a need to increase respiratory function exercise adherence among elderly patients with frailty and tuberculosis who have a high incidence of depression. Medical staff should assess adverse emotions in patients and their adherence to respiratory function exercises on a periodic basis.

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To Analyze the Influencing Factors of Senile Coronary Heart Disease Patients Complicated with Frailty Syndrome

Cited by 6 publications

References 19 publications

Incidence of frailty and construction of prediction model in elderly male patients with chronic obstructive pulmonary disease

Incidence of frailty and construction of prediction model in elderly male patients with chronic obstructive pulmonary disease

Chronic Coronary Syndrome in Frail Old Population

Correlation between depression and adherence to respiratory function exercise in elderly frail patients with tuberculosis: A cross-sectional survey

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