Abstract:Infection with the bacteria Borrelia burgdorferi results in a multidimensional disease including, fever, headache, arthritis, and a characteristic skin rash. When left untreated, bacteria can disseminate to multiple parts of the body including joints, heart, and nervous system. Approximately 10–20% of patients treated with antibiotic therapy for Lyme disease will continue to have persistent symptoms for months or years. T cells predominate the immune response in the synovial fluid of these patients; however, t… Show more
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