Titrations in Nonaqueous Solvents

Abstract

A lthoughthere have been no dra-_£\_ matic "breakthroughs" during the last two years there has been notable advance in several areas. Particularly gratifying is the number of outstanding papers devoted to the fundamentals of nonaqueous equilibria. Not only are some of the more commonly used solvents such as acetonitrile receiving continued attention, but theoretical studies are being extended to solvents of very low7 dielectric constant. There appears to be a trend toward utilizing the newer types of measurements such as nuclear magnetic resonance and toward using several different types of measurements in the same investigation. In some of the recent work, for example, one finds spectrophotometric, conductometric, potentiometric, and solubility measurements combined to achieve an understanding not possible with a single technique. In the area of study concerned with the effect of solvent and acid structure on acidity, new and imaginative ideas have been introduced.

Titrations in Nonaqueous Solvents

“…The hydration of ions in acetonitrile was studied by Chantooni and Kolthoff (87). Equations were developed which permit the calculation of hydration constants from the solubility product of a slightly soluble salt and the total ionic solubility in the presence of varying concentrations of water.…”

Potentiometric Titrations

“…Harlow (92) has discussed the effect of potassium ion on the shape of potentiometric titration curves when very weak acids are titrated in nonaqueous solvent. The r e d t s obtained depend on the type of glass electrode employed, its pretreatment, the amount of acid being titrated, and the potassium content of the titrant.…”