Titanium surface modified by hydroxyapatite coating for dental implants

Hung, Kuo-Yung; Lo, Shou-Chih; Shih, Chung-Sheng; Yang, Yaxiong; Feng, Hui; Lin, Yi-Chih

doi:10.1016/j.surfcoat.2012.03.037

Cited by 97 publications

(45 citation statements)

References 15 publications

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“…Thereby, focus can be made on the development of Ca-P-based surface coatings on titaniumbased materials for load-bearing implant applications. Typical coating methodologies like sandblasting [10,11], plasma spraying [12][13][14], alkaline treatment [15], acid etching [16], laser surface treatment [17][18][19], anodic oxidation [20] and MAO [21,22] are extensively studied at laboratory scale. Compared with other surface modification techniques, MAO is one of the most applicable methods to deposit a porous bioceramic layer on Ti and its alloys.…”

Section: Introductionmentioning

confidence: 99%

Review of the biocompatibility of micro-arc oxidation coated titanium alloys

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Review of the biocompatibility of micro-arc oxidation coated titanium alloys

et al. 2015

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“…Combining the sputtering technique with HA and SLA surface treatments can promote the biocompatibility and stability of dental implants. Although HA sputter targets are commercially available, the authors previously developed an atmospheric plasma-sprayed (APS) HA target [17] that can be used to perform sputtering processes [18].…”

Section: Introductionmentioning

confidence: 99%

Characteristics of RF-Sputtered Thin Films of Calcium Phosphate on Titanium Dental Implants

2017

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Hydroxyapatite (HA) coatings on titanium have been investigated for many years, and have demonstrated advantageous biocompatibility in dental implants. Animal experiments have demonstrated that the biological response to plasma-sprayed HA-coated implants shows disadvantages in terms of adherence, thickness uniformity, and long-term osseointegration effects. Determining how to resolve the degradation problem of HA in the body by improving osseointegration and stability in alveolar bones has become an increasingly researched topic. The present study investigated the film characteristics and dissolution properties of calcium phosphate (CaP) coatings obtained by radio-frequency (RF) sputtering of a self-developed atmospheric plasma spray (APS) HA target. The experimental parameters varied, including RF power (60-250 W), sputtering time (15-120 min), and substrate roughness (0.4-4 µm). Analyses were conducted using synchrotron X-ray diffraction, Fourier transform infrared spectroscopy (FTIR), white light interferometry, and scanning electron microscopy combined with energy-dispersive X-ray spectroscopy (EDS). EDS analysis showed that the Ca/P ratio increased as the discharge power was increased. The analysis results also showed that a lower surface roughness resulted in higher crystallinity, because a larger surface-free energy was attained during sputtering. In-plane texturing has been proven when HA films are sputtered onto substrates of varying roughness, within appropriate deposition parameters. FTIR analysis revealed the presence of the principal PO 4 3− bonds in the deposited calcium phosphate films. The CaP films induced calcium phosphate precipitation when immersed in simulated body fluid (SBF), suggesting that, based on in vitro bioactive behavior, the proposed combined surface modification can be used in dental implants.

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“…Therefore, controlling the respective populations of epithelial and mesenchymal stem cells to shift the balance in favor of mesenchymal stem cells could help to ensure osseointegration. To date, various surface modifications have been developed, such as sandblasting and acid etching (SLA), hydrothermal hot pressing, laser pulse, dip coating, and spray plasma coating [16,17,18,19,20,21,22,23,24,25,26]. However, as yet, no method has been devised to regulate cell populations in functional dental implants.…”

Section: Discussionmentioning

confidence: 99%