Tissue Staining

Fennerty, M. Brian

doi:10.1016/s1052-5157(18)30506-3

Cited by 47 publications

(35 citation statements)

References 44 publications

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“…Chromoendoscopy has been proposed as the best way to identify colonic lesions at colonoscopy [18,24,25]. However, detection rates for colorectal lesions have been investigated in only three randomized controlled trials using pan-colonic chromoendoscopy with indigocarmine [10,12,26].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of chromoendoscopy with indigocarmine for the detection of ascending colon and cecum lesions

Park

Lee

Han

et al. 2008

Scandinavian Journal of Gastroenterology

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Section: Discussionmentioning

confidence: 99%

Efficacy of chromoendoscopy with indigocarmine for the detection of ascending colon and cecum lesions

Park

Lee

Han

et al. 2008

Scandinavian Journal of Gastroenterology

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“…Chromoendoscopy involves the topical application of stains or pigments to improve tissue localization, characterization, or diagnosis during endoscopy [Fennerty, 1994]. Chromoendoscopy with methylene blue has been studied in Barrett's patients.…”

Section: Chromoendoscopymentioning

confidence: 99%

Review: Diagnosis and management of Barrett’s esophagus for the endoscopist

Garud

Keilin

Cai

et al. 2010

Therap Adv Gastroenterol

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In Barrett's esophagus, the stratified squamous epithelium lining the esophagus is replaced by specialized intestinal-type columnar epithelium. The prevalence of Barrett's esophagus has ranged from 0.9% to 4.5%. The rate of progression from Barrett's esophagus to esophageal adenocarcinoma is 0.5% per patient-year. Proton-pump inhibitors are the mainstay of symptom control in Barrett's patients. Nondysplastic Barrett's and Barrett's with low-grade dysplasia (LGD) are typically managed by periodic surveillance. Radiofrequency ablation is being evaluated as a modality for managing nondysplastic Barrett's and Barrett's with LGD. The options for the management of Barrett's patients with high-grade dysplasia (HGD) include endoscopic therapy, surgery, and intensive surveillance until biopsy reveals adenocarcinoma. Endoscopic therapy involves endoscopic mucosal resection (EMR) and ablation. More aggressive techniques such as endoscopic submucosal dissection and larger segment endoscopic mucosal resection are under study. In this review, we discuss the diagnosis and management of Barrett's esophagus. The recommendations from the major gastroenterologic societies and the current and investigational endoscopic modalities for the management of Barrett's esophagus with and without dysplasia are reviewed.

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“…There are numerous different dyes used in the gastrointestinal tract and they can be classified based on specific characteristics, i.e., absorptive, reactive, and contrast stains. 19,23,25 Endoscopists have mainly used indigo carmine and methylene blue and sometimes cresyl violet for enhancing visualization of the mucosa in the colon (Table 1). 26 -28 …”

Section: Chromoendoscopymentioning

confidence: 99%

“…Indigo carmine is not absorbed and therefore can be used for dye contrast staining. 19,25 The application of dye is generally performed during the endoscopic examination via a spraying catheter, 25,26 or the indigo carmine solution could be flushed through the biopsy channel using a syringe and air. 27 Because of gravity, the solution pools in areas of depressions and ulcerations and fills the crevices and valleys between mucosal projections.…”

Section: Indigo Carminementioning

confidence: 99%

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Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease

Thorlacius

Tóth

2007

Inflammatory Bowel Diseases

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Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. However, it is now generally accepted that neoplastic changes in colitis are frequently flat and depressed, which are easily missed by use of routine colonoscopy. The introduction of chromoendoscopy, especially in combination with magnifying endoscopy, has greatly advanced our means to detect and differentiate neoplastic lesions in the colorectum. Accumulating evidence-based data indicate that implementation of chromoendoscopy into colon cancer surveillance protocols for patients with inflammatory bowel disease is effective. However, the introduction of chromoendoscopy into surveillance programs requires meticulous training and further studies to compare the value of chromoendoscopy to newer endoscopic devices and techniques, such as narrow band imaging.

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Tissue Staining

Cited by 47 publications

References 44 publications

Efficacy of chromoendoscopy with indigocarmine for the detection of ascending colon and cecum lesions

Efficacy of chromoendoscopy with indigocarmine for the detection of ascending colon and cecum lesions

Review: Diagnosis and management of Barrett’s esophagus for the endoscopist

Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease

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