2017
DOI: 10.7454/uiphm.v1i0.48
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Tissue Response of TM-Joint to Arthritis Induction Methods in Rat

Abstract: Objective: Pathogenesis of rheumatoid arthritis (RA) related temporomandibular joint disorder remains unclear. Some studies investigated the change of condyle after Complete Freund's Adjuvant (CFA) injection which is similar to osteoarthritis. However, there were few studies to demonstrate effect of TMJ in CIA which mimics RA. The aim of this study was to investigate the TM-joint response of CFA and CIA group in rat model. Methods:24 Rats were divided into 4 groups. (1) Control group. (2) 50μl type I collagen … Show more

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