Abstract:Background: Juvenile nasopharyngeal angiofibroma (JNA) has a high recurrence rate a er surgery. Cofilin overexpression is associated with increased tumor cell metastasis, and progression of various human cancers. However, studies on cofilin expression in JNA are rare. The purpose of this study was to investigate the expression and localization of cofilin in a tissue microarray (TMA) of JNA specimens. In addition, we also analyzed its correlation with clinicopathological features and recurrence.
Methods:Immunoh… Show more
“…Similarly, juvenile nasopharyngeal angiofibroma (JNA) may recur after surgery. In this regard, Li et al . indicated that cofilin was an independent prognostic marker for JNA recurrence and might be a novel therapeutic target for extensive JNA.…”
“…Similarly, juvenile nasopharyngeal angiofibroma (JNA) may recur after surgery. In this regard, Li et al . indicated that cofilin was an independent prognostic marker for JNA recurrence and might be a novel therapeutic target for extensive JNA.…”
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