Tissue Homeostasis of the Myocardium in Newborn Albino Rats Exposed to Intrauterine Hypoxia

Kryzhanovskaya, S. Yu.; Сазонова, Е. Н.; Тимошин, С. С.

doi:10.1023/b:bebm.0000046928.79653.10

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some studies [ 19 ] have shown that intermittent or continuous severe hypoxia can lead to an earlier and greater degree of inflammatory response and cell damage in the heart. A previous study suggested that hypoxia can regulate morphological changes and remodeling of the myocardium and can present as wall thickening [ 20 ], suggesting that the thickening of the cardiac wall observed in the patients in this study may not only be the result of the immune response, but that hypoxia may also cause changes in ventricular morphology. Fewer patients presented with right heart enlargement, a thickened right-ventricular wall, and decreased right heart function.…”

Section: Discussionmentioning

confidence: 70%

Cardiac manifestations of COVID-19 in Shenzhen, China

Zeng

et al. 2020

Infection

View full text Add to dashboard Cite

Purpose The coronavirus disease 2019 (COVID-19) outbreak has become a global public health concern; however, relatively few detailed reports of related cardiac injury are available. The aims of this study were to compare the clinical and echocardiographic characteristics of inpatients in the intensive-care unit (ICU) and non-ICU patients. Methods We recruited 416 patients diagnosed with COVID-19 and divided them into two groups: ICU (n = 35) and non-ICU (n = 381). Medical histories, laboratory findings, and echocardiography data were compared. Results The levels of myocardial injury markers in ICU vs non-ICU patients were as follows: troponin

show abstract

Section: Discussionmentioning

confidence: 70%

Cardiac manifestations of COVID-19 in Shenzhen, China

Zeng

et al. 2020

Infection

View full text Add to dashboard Cite

show abstract

Effects of Antenatal Hypoxia on Tissue Homeostasis in the Myocardium of Albino Rats: Early and Delayed Consequences

et al. 2014

Self Cite

View full text Add to dashboard Cite

Body weight, absolute and relative heart weight, DNA-synthetic activity of cardiomyocytes, and number of nucleoli in cardiomyocyte nuclei were reduced in newborn albino rats exposed to antennal hypoxia. All these changes developed against the background of oxidative stress. In mature animals, the absolute and relative heart weights were decreased, but the ratio of mononuclear cardiomyocytes in both ventricles was higher than in the control. These changes were accompanied by an increase in the percent of collagen fibers in the myocardial stroma. In the right ventricle, an increase in the cardiomyocyte length to width ratio and a decrease in the number of nucleoli were found. The observed changes can probably induce heart function disturbances under pathological conditions.

show abstract

Tissue Homeostasis of the Myocardium in Newborn Albino Rats Exposed to Intrauterine Hypoxia

Cited by 2 publications

References 0 publications

Cardiac manifestations of COVID-19 in Shenzhen, China

Cardiac manifestations of COVID-19 in Shenzhen, China

Effects of Antenatal Hypoxia on Tissue Homeostasis in the Myocardium of Albino Rats: Early and Delayed Consequences

Contact Info

Product

Resources

About